ClinQC

ClinQC is an integrated and user-friendly pipeline for quality control, filtering and trimming of Sanger and NGS sequencing data for hundred to thousands of samples/patients in a single run in clinical research. It can analyze raw sequencing data and produces unified output as FASTQ files per sample/patient with Sanger quality encoding. First, ClinQC convert input read files from their native formats to a common FASTQ format and remove adapters, and PCR primers. Next, it split barcoded samples, filter duplicates, contamination and low quality sequences and generates a QC report.