claude-prism

ClaudePrism is an open-source, local-first scientific writing application that combines LaTeX editing, Python analysis, and Claude AI assistance. It provides researchers with a desktop environment for preparing papers, theses, presentations, and other academic documents. An embedded Tectonic compiler renders LaTeX projects offline after required packages are cached. Its Python environment supports scientific computation, data visualization, and package management through uv. More than 100 specialized scientific skills cover bioinformatics, machine learning, clinical research, and other disciplines. The integrated Claude assistant supports document editing, research workflows, and contextual questions about figures or equations. Git-based history preserves document versions and allows users to review proposed changes. Files remain locally stored, while AI requests are processed through Anthropic's API.