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CHANCE-HT is a ChIP-seq pre-processing software that filters samples with weak IP-strength, identifies heavily biased control experiments and under sequenced samples, detects batch effects, and normalizes large ensembles of ChIP-seq datasets. CHANCE-HT uses a parallel processing approach to normalize and filter large collections of ChIP-seq datasets in tandem.
Features
- Multi-sample normalization
- IP-strength estimation
- Quality control
- Bias detection
- Batch effect detection
- Parallel processing of large ensembles of datasets
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