BiRW

The availability of ontologies and systematic documentations of phenotypes and their genetic associations has enabled large-scale network-based global analyses of the association between the complete collection of phenotypes (phenome) and genes. BiRW is a package designed for analysis and prediction of the phenome-genome associations. BiRW package contains a program for analysis of circular bigraphs (CBGs) and the bi-random walk (BiRW) algorithm to capture the CBG patterns in the networks for unveiling human and mouse phenome-genome association. The processed OMIM human disease phenotype-gene association network and MGI mouse phentoype-gene association network are also released together with the source code.