This work provides an efficient tool (QcReads) for trimming adapter sequences and low quality sequences, in raw reads generated by the high throughput sequencing platforms. This will help to make use of data sequenced from poorly constructed DNA/cDNA libraries. The mapping ratios increase remarkably after QcReads trimming.
Citation: Ma, Y., Xie, H., Han, X., Irwin, D.M., and Zhang, Y.P. (2013). QcReads: an adapter and quality trimming tool for next-generation sequencing reads. J Genet Genomics 40, 639-642.

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2013-11-06