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From: Chambers, M. <mat...@gm...> - 2026-05-26 15:03:42
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Hi Magnus, A couple years ago I flipped msconvert from needing the -z flag to turn on zlib compression to turning it on by default, which means you need "--zlib=off" to turn it off. There's just not that many tools that don't support compression, and it makes a huge difference in output file size. If you use the --zlib=off flag and still get compressed files let me know that's definitely a bug. Hope this helps, -Matt On Mon, May 25, 2026 12:33 PM EDT (-0400), Brian Pratt wrote: > Hi Magnus, > > That would be surprising - are you certain of this? What are you seeing from the downstream application? Do your mzML files contain > anything like the following? > > <binaryDataArray encodedLength="1863392"> > <cvParam cvRef="MS" accession="MS:1000523" name="64-bit float" value=""/> > *<cvParam cvRef="MS" accession="MS:1000574" name="zlib compression" value=""/>* > <cvParam cvRef="MS" accession="MS:1000514" name="m/z array" value="" unitCvRef="MS" unitAccession="MS:1000040" unitName="m/z"/> > > Best regards, > > Brian Pratt > > On Mon, May 25, 2026 at 1:13 AM Magnus Sellstedt <mag...@um...> wrote: > > Hello, > > I am using msconvert to convert Agilent d.files to uncompressed mzML-files. This has worked fine previously, but after a download of a > recent version of msconvert, the mzML-files now appear to be somewhat compressed regardless of if I turn zlib-compression on or off > via the GUI. My downstream application does not work on compressed files. How can I generate the uncompressed mzML-files? > > Best > Magnus Sellstedt > _______________________________________________ > proteowizard-support mailing list > pro...@li... > https://lists.sourceforge.net/lists/listinfo/proteowizard-support > > > > _______________________________________________ > proteowizard-support mailing list > pro...@li... > https://lists.sourceforge.net/lists/listinfo/proteowizard-support |