Re: [proteowizard-support] MSconvert timsTOF data

[Chambers, M. <mat...@gm...>]

Hi Wenguang,

Only MzML and mz5 support official storage of ion mobility information. MGF supports it unofficially using the TITLE string, but that's a 
free text string with no guarantee software will be able to understand it.

With the --combineIonMobilitySpectra option and outputting to mzML, timsTOF data can be stored much more compactly because each frame is 
just 1 spectrum with an extra array of ion mobilities (one ion mobility for each peak), but I don't think many software packages support 
that representation yet.

Hope this helps,
-Matt


On 6/18/2019 12:04 PM, Wenguang wrote:
> Dear MSconvert team,
>
> I am currently using MSconvert (version 3.0.19070) to convert raw timsTOF data. It seems currently msconvert only supports MGF format to 
> keep the ion mobility information.
>
> I am wondering whether it supports mzXML files as well, so that I can use TPP workflow using mzXML files that contain ion mobilities as well.
>
> Thank you very much for your help in advance.
>
> Best regards,
> Wenguang