Re: [micro-manager-general] confocal upgrade suggestion

[PAVAK S. <pa...@uc...>]

It depends very much on the specific bells and whistles. I would account
for anywhere from $100k - $500k+ for the upgrade depending on the specific
scanner, laser lines, cameras, software etc. There are some systems on the
market that can come in cheaper using LED or arc lamp excitation, but I am
less familiar with their performance and specific price points.

Your Nikon rep or any of the third party integrators will be able to give
you a rough ball park pretty quickly based on your needs and you can decide
if it's in the realm of possibility for your budget.

Best,
Pavak


On Wed, Feb 19, 2020, 3:58 PM Yanfei Jiang <yan...@gm...> wrote:

> Hi Pavak
> As I understand, multi point options are usually more expensive, right?
> how much am I expecting for such a system? thanks
>
> Yanfei
>
> On Mon, Feb 17, 2020 at 8:31 PM PAVAK SHAH <pa...@uc...> wrote:
>
>> Are you limiting consideration to a point scan confocal?
>>
>> There are lots of multi-point options from Nikon and third party
>> integrators including spinning disk confocals based on the Yokogawa CSU-X1
>> and W1, the Andor Dragonfly, the Crest Optics X-Light, and others. Also
>> similar options based on analog SIM (no need for multiple images or
>> computational post processing for resolution improvement) such as the
>> Yokogawa CSU-SoRa and the Visitech iSIM (I include the SoRa for
>> completeness but personally found it to be optically inferior to the iSIM
>> when demoed, disclaimer: I used VisiTech's first commercial iSIM as a
>> postdoc and have since bought one for my own lab).
>>
>> For live imaging of nearly any sort or cases where speed or gentleness is
>> desired, a spinning disk or multi-point confocal is very much worth
>> considering over a point scan system.
>>
>> Best,
>> Pavak
>>
>> On Fri, Feb 14, 2020, 3:24 PM Yanfei Jiang <yan...@gm...> wrote:
>>
>>> Dear MM community,
>>>
>>>  Our lab is considering upgrade a nikon Ti2E microscope to have confocal
>>> capability. I am wondering what options do I have besides Nikon. I saw
>>> Thorlabs has one, any other companies? Thanks a lot
>>>
>>> Yanfei Jiang
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>>> https://lists.sourceforge.net/lists/listinfo/micro-manager-general
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