Download
MethylExtract is a user friendly tool to generate i) high quality, whole genome methylation maps and ii) to detect sequence variation within the same sample preparation. The program is implemented into a single script and takes into account all major error sources: sequencing errors, bisulfite failure, clonal reads and single nucleotide variants. MethylExtract detects variation (SNVs – Single Nucleotide Variation) in a similar way than VarScan, a very sensitive method extensively used in SNP and genotype calling based on non-bisulfite treated reads.
Features
- Methylation and SNV calling from NGS BS-Seq experiments
- Detects and removes potential PCR duplicates
- Putative bisulfite failures detection
- Sequencing errors control
- Statistical bisulfite failure assessment
- Bisulfite SAM / BAM files processing
- Multithreading and memory control
Categories
Bio-InformaticsFollow MethylExtract
Other Useful Business Software
Get the most trusted enterprise browser
Defend against security incidents with Chrome Enterprise. Create customizable controls, manage extensions and set proactive alerts to keep your data and employees protected without slowing down productivity.
Rate This Project
Login To Rate This Project
User Reviews
Be the first to post a review of MethylExtract!