Due to a limitation of the mouse protocol, columns beyond 223 (and, in case of joe, columns beyond 208 for whatever reason) can't be clicked.
Luckily, there's an extension to overcome this limitation, initially implemented by rxvt-unicode, later added by iterm2, vte (gnome-terminal) and xterm; hopefully more to come.
For technical details, see http://www.midnight-commander.org/ticket/2662
The attached patch causes joe's mouse to work on arbitrary coordinates, even beyond 208, if the underlying terminal supports this. If the terminal does not support this extension, the patch causes no harm, mouse handling still works for coordinates up to 208.