In Trinsic, the avatar is unable to enter any bulidings except the stables without the game quitting. Needless to say this is a bit of a stumbling block to game satisfaction. I use a Powerbook 333 running OS 8.6 with 96RAM. Keep up the good work - This is one of the best games ever and about time it came to MAC.
My guess would be that this is an audio issue. Have you tried disabling sound effects in the configuration file?
This works fine for me. Only guess might be that you have to increase the assigned memory partition.