Flying Hawk - 2017-06-08

Turning off compression wouldn't help. What most responsible for changing your whole file isn't compression, it's encryption.

With compression but without encryption, all the data blocks following the changed block would be changed, but blocks that come before stay the same.

With encryption, with or without compression, every block in your file would be changed, even if the original file stay exactly the same. Because 7zip uses AES with CBC mode, which uses an initialization vector (IV) that should be different each time you re-encrypt something. A different IV changes every block in your data.

I'm not sure why you'd want your TrueCrypt container to be again encrypted by CryptSync / 7zip. I don't think there's a meaningful increase in security.