Easy to use Python library for creating 2D arcade games
Pymunk is a easy-to-use pythonic 2d physics library
Modern OpenGL binding for Python
Pycraft is an open-source, OpenGL based game made in Python
Python+Numpy+OpenGL, scalable and beautiful scientific visualization
ZED OS the clone of Windows XP
Test project with a 2D platform game developing in Godot 3.1
A fast, powerful and adaptable GUI solution
Pygrid is an open-source and cross-platform pygame/python 2D engine.
A graphics engine + toolkit.
Cross platform 2D game creation framework with Python bindings
Access to Irrlicht Engine SDK from assembler, C, Python, Basic, Pascal