Showing 114 open source projects for "sequence scaffold, java"

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  • 1

    scFvMiner

    Scripts for analysing NGS data

    These scripts written in java can be used for deep sequencing analysis of the scFv antibodies from a synthetic antibody library and yields complete sequence information on the randomized areas of antibodies enriched from the library by phage display. The methods are descriped in Lövgen, J., Pursiheimo, J.P., Pyykkö, M., Salmi, J. & Lamminmäki, U. (2016) Next generation sequencing of all variable loops of synthetic single framework scFv – application in anti-HDL antibody selections. ...
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  • 2
    KAnalyze

    KAnalyze

    DNA/RNA Sequence K-mer Toolkit

    KAnalyze is a Java toolkit designed to convert DNA and RNA sequences into k-mers. It is both a command line application and an API.
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  • 3
    Mauve computes and interactively visualizes genome sequence comparisons. Using FastA or GenBank sequence data, Mauve constructs multiple genome alignments that identify large-scale rearrangement, gene gain, gene loss, indels, and nucleotide substutit
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  • 4
    SILA

    SILA

    Automated bacterial and archaeal genome annotation system

    SILA is a system for automated annotation of bacterial and archaeal genomes. It provides accurate gene prediction using a combination of tools (Prodigal and HGF) and a web site for task management and visualization of annotation. This project is in alpha stage. Please use the online service available at: http://www.bioinfo.ufpr.br/SILA/login.jsp Documentation (portuguese only): http://hdl.handle.net/1884/34801
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  • 5

    Sequencia

    Protein Primary Sequnece Analysis

    The current work is focused on the Software Development of an Offline Tool for “PRIMARY-SEQUENCE ANALYSIS” with JAVA and open source resources. SEQUENCIA Tool is an offline Tool of Primary Sequence Analysis, which is quite prevalent Topic for Researchers all over the world. Sequence Name, Sequence Length, Absorbance, Net charge, Iso electric charge, Amino acid composition, Amino acid classification, Aliphatic Index, Instability Index, Average Hydropathy etc are the Primary Sequence Analysis related Attributes for which this Tool exist. ...
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  • 6
    The Protein Similarity Network

    The Protein Similarity Network

    Human protein similarity network used to predict drug safety.

    This is the protein similarity network - PSIN. Here, the nodes are human proteins and they are linked only if they share considerable sequence similarity. We found that this network is particularly useful to distinguish approved from problematic drug-targets. Here you also find the complete set of programs and datasets we used for this purpose. Free to help further test and develop this project. Your help and expertise are much appreciated ! If you have any questions, please do...
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  • 7

    xorlisp

    Bit level lambda continuations and nothing else - Queue automata

    Not working yet. To deal with the Halting Problem, computing and data are navigated using debugger ops: linearForward and treeForward, which navigate an astronomically large bit string where 1 is ( and 0 is ). All pairs are derived from (). For example, true is represented as ((()())()), and false is (()(()())). It appears related to the church encoding of lambda where T chooses first parameter and F chooses second, of a pair. Continuations are nearly finished code and are represented as a...
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  • 8
    GESPA

    GESPA

    Accurately predicts disease association of single nucleotide mutations

    ...The software can be used clinically to determine if observed nsSNPs are associated with disease. A host of annotations are provided: orthologous and paralogous multiple sequence alignments, UCSC annotations, reports detailing conservation of a nsSNP in alignments, and links to external nsSNP and gene information such as relevant publications. GESPA is connected to a constantly updating SQL server allowing for fast data retrieval. NOTE: REQUIRES Java 1.7.0+. Port 1433 cannot be blocked by firewall, network, or antivirus program. ...
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  • 9
    GenomeView
    GenomeView is a genome browser and annotation editor that displays reference sequence, annotation, multiple alignments, short read alignments and graphs. Most major data formats are supported. Local and internet files can be loaded. This project has moved to GitHub: https://github.com/GenomeView/genomeview
    Downloads: 1 This Week
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  • 10

    TE-locate

    a tool for calling transposons

    TE-locate is a tool to locate all copies of sequences in a reference sequence using read-pairs. TE = Transposable Element Input is NGS-data. Please download all files first (including the demo data) and make your first run then.
    Downloads: 3 This Week
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  • 11
    ALTER is a web-based tool to transform between multiple sequence alignment formats. ALTER focuses on the specifications of mainstream alignment and analysis programs rather than on the conversion among more or less specific formats.
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  • 12

    HomSI

    Homozygous Stretch Identifier from next-generation sequencing data

    In consanguineous families, as a result of inheriting the same genomic segments through both parents, the individuals have stretches of their genomes that are homozygous. This situation leads to the prevalence of recessive diseases among the members of these families. Homozygosity mapping is based on this observation and several recessive disease genes have been discovered with the help of this technique in consanguineous families. The researchers typically use SNP arrays to determine the...
    Downloads: 1 This Week
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  • 13
    MNCubes

    MNCubes

    Research project to compute repeating patterns in discrete planes

    A 2D line can be rasterized into a 8-connected sequence of pixels which exhibit repeating patterns of connected pixels. Likewise, a 3D plane can be rasterized into connected cubes. A 'rectangular' cut of m x n cubes is a (m,n)-cube. Given m and n, the goal of this project is to generate all the (m,n)-cubes for all the (integer) discrete planes, based on the intersection vertices on a Farey diagram.
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  • 14
    vipR is a program to screen for sequence variants (SNPs, deletions) in sequence data generated by high-throughput-sequencing platforms. Information on this and other projects can be found on: http://www.altmann.eu
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  • 15
    GenoCAD
    GenoCAD is a CAD software for synthetic biology. This application provides a web-based tool to design plasmids, artificial gene networks, and other synthetic genetic systems composed of standard genetic parts. It includes a parts management system, a rule-based design tool, and a simulation engine. This project has morphed into a SaaS model. The open source code is no longer maintained.
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  • 16

    x2fasta

    Tools for reformatting common sequence formats into fasta

    A collection of tools to transform common biosequence formats (e.g. EMBL, SWISS-PROT, UniProtKB, GenBank and RefSeq) into the fasta sequence format.
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  • 17
    FSA is a probabilistic multiple sequence alignment algorithm which uses a "distance-based" approach to aligning homologous protein, RNA or DNA sequences.
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  • 18
    PlaTypUS

    PlaTypUS

    Plasmodium Typing Utility Software

    The goal of PlaTypUS is to establish a unified Plasmodium whole genome analysis tool, that aligns short read sequences in an agreed upon manner, with many quality control steps, and calls both SNVs and CNVs in a community agreed standard way. We also seek to provide this analysis in a stand-alone graphic user interface so that labs around the world can analyze their own whole genome sequencing data, rather than relying on outside institutes.
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  • 19

    EDNA

    Energy Based Multiple Sequence Alignment (MSA) for Binding Sites

    Multiple Sequence Alignment for Transcription Factor Binding Sites using Di nucleotides dependencies and relying on Free Interaction energies between neighbouring DNA bases to stabilise substitution energy of the alignment. http://www.ncbi.nlm.nih.gov/pubmed/23990411
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  • 20

    DimerRemover

    Remove adapter dimers from NGS data

    This program can be used to count or remove adapter dimers in fastq files. Using a provided adapter sequence, it generates variations of this sequence and stores them in a hash table. The reads can then be directly matched against the hash. It is far more time efficient than doing alignment.
    Downloads: 0 This Week
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  • 21
    SecStAnT

    SecStAnT

    Secondary Structure Analysis Tool for data selection and statistics

    SecStAnT is a tool for the automatic creation of data-sets of structures from Protein Data Bank (PDB) with user-defined structural composition, and for the calculation of their internal variables distributions. SecStAnT is able to 1. Select from PDB data sets of structures based on user specified secondary structures (defined based on internal PDB classification or on DSSP) and/or sequence motives. 2. Build Data-sets at different levels of resolution (all atoms, only backbone, only...
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  • 22
    DocCO

    DocCO

    Non-disjoint groupping of Documents based on word sequence approach

    This is a GUI for learning non disjoint groups of documents based on Weka machine learning framework. It offers the possibility to make non disjoint clustering of documents using both vectorial and sequential representation (word sequence approach based on WSK kernel). All data format supported by WEKA could be used in DocCO. Data could be loaded from files, from databases or from specified URL. All the preprocessing techniques implemented in WEKA could be used before performing the learning.
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  • 23
    ADOPS

    ADOPS

    Automatic Detection Of Positively Selected Sites

    ADOPS is a bioinformatics tool that automatizes the detection of positively selected sites given a set of unaligned nucleotide sequence data. ADOPS implements a complete workflow that integrates three well-known bioinformatic tools: T-Coffee, MrBayes and Codeml (PAML).
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  • 24
    GEPETTO - Gene Prioritization in Java

    GEPETTO - Gene Prioritization in Java

    GEPETTO (GEne Prioritization ExTended TOol)

    ...It takes advantage of the data integration capabilities in the SM2PH-Central Framework(KD4v,MSV3d,BIRD,..), combined with in-house developed gene prioritization methods. It currently incorporates six prioritization modules, based on gene sequence, protein-protein interactions, gene expression, disease-causing probabilities, genomic context). GEPETTO is written in Java/Python and supported by an advanced modular architecture, which means that it can easily be modified and extended by the user, in order to include alternative scoring methods and new data sources. We intend to extend the system from gene-level to variant-level prioritization, by exploiting the variant data in the MSV3D database. ...
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  • 25
    An assessmemt tool of sequence repeats for short read sequencing.
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