Showing 2481 open source projects for "informatics"

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  • 1
    Nifty Reg
    This project, initially developed at University College London, contains programs to perform rigid, affine and non-linear registration of nifti or analyse images. Two versions of the algorithms are included, a CPU- and a GPU- (using CUDA) based implementation.
    Downloads: 6 This Week
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  • 2

    PPLine

    SNP calling, annotation and gene/transcripts expression quantification

    PPLine is a Python-based suite aimed to process raw RNA-seq or Exome-seq data. PPLine provides: - read mapping (STAR/Tophat2/bowtie/bowtie2), including novel splice junsctions discovery - gene and transcript expression estimation (HTSeq-count/Cufflinks) - SNP calling with BQSR and indel realignment (samtools/GATK) - variant annotation (Annovar) - novel transcripts discovery (Cufflinks) - predicting proteotypic peptides and creating ref/alt proteins fasta-database - integration of...
    Downloads: 1 This Week
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  • 3

    QMinim

    A web-based minimisation service

    Based on MinimPy (http://sourceforge.net/projects/minimpy/), QMinim is a web-based minimization application, for allocation of subject to different arms of a clinical trial. It is an alternative to randomization, with the advantage of balancing arms of trial with respect to preselected prognostic factors. All aspects of minimization procedure including treatments, factors, minimization protocole, and including a preload can be customized using QMinim.
    Downloads: 0 This Week
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  • 4
    Niche Analyst (NicheA) was developed based on the BAM framework which allows users to create virtual spaces and virtual species, and to analyze ecological niches in both multivariate environmental and geographic spaces, linking views of the niche in the two spaces. The unique functionality in NicheA, not available in other software programs, is estimating Grinnellian niches of species based on environmental variables and occurrence records, but with a clear focus on fundamental ecological...
    Downloads: 11 This Week
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  • 5

    BEMoDA

    Dissolution profile comparison Model Dependent-Independent Approach

    Dissolution profile comparison (Biowaiver aid) Model Dependent-Independent Approach scripts for in-vitro dissolution profile comparison as proposed by Sathe et al. in 1996 (Sathe PM, Tsong Y, Shah VP. In-vitro dissolution profile comparison: statistics and analysis, model dependent approach. Pharm Res. 1996 Dec;13(12):1799-803) and Tsong et al. in 1996 (Tsong Y, Hammerstrom T, Sathe P, Shah VP. (1996) Statistical Assessment of Mean Differences between Two Dissolution Data Sets, Drug Info. J....
    Downloads: 0 This Week
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  • 6
    HCS Analyzer

    HCS Analyzer

    High Content Screening Analyzer

    HCS Analyzer is an open source software dedicated to High Content Screening data processing and analysis.
    Downloads: 0 This Week
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  • 7

    GAPE

    proteogenomic analysis software

    GAPE is a one-stop proteogenomic informatics software that provides a multifaceted and standard workflow against eukaryotes in proteogenomic data-analysis cycle for genome refinement and global identification of PTM events. This software allows concurrent querying of proteomic and genomic databases to refining the genome and proteome annotations comprehensively. This includes MS data and database construction, database searches, FDR calculations, statistical result integration, validation of annotated genes, identification of previously unidentified genes, protein level identification of alternative spliced variants and SAAV, biological interpretation, and global PTM discovery.
    Downloads: 1 This Week
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  • 8

    SimPhospho

    Proteomics software for simulation of spectra of phosphopeptides

    Downloads: 0 This Week
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  • 9

    BisSNP

    Bisulfite-seq/NOMe-seq SNPs & cytosine methylation caller

    Now in Github: https://github.com/dnaase/Bis-tools/tree/master/Bis-SNP BisSNP is a package based on the Genome Analysis Toolkit (GATK) map-reduce framework for genotyping in bisulfite treated massively parallel sequencing (Bisulfite-seq, NOMe-seq and RRBS) on Illumina platform. It uses bayesian inference with either manually specified or automatically estimated methylation probabilities of different cytosine context(not only CpG, CHH, CHG in Bisulfite-seq, but also GCH et.al. in other...
    Downloads: 5 This Week
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  • 10
    A collaborative platform for non-protein-coding RNA annotation.
    Downloads: 0 This Week
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  • 11
    EnzymeFinder

    EnzymeFinder

    This is a bio-informatic project for finding enzyme

    This is a bio-informatic project for finding enzyme. It is only free for academic and non-commercial users. Any commercial use should obtain our permission. Please contact wugang@ise.neu.edu.cn or ccdatabank@hotmail.com.
    Downloads: 0 This Week
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  • 12

    lr2rmats

    Long read to rMATS

    lr2rmats is a Snakemake-based light-weight pipeline which is designed to utilize both third-generation long-read and second-generation short-read RNA-seq data to generate an enhanced gene annotation file. The newly generated annotation file could be provided to rMATS for differential alternative splicing analysis. More information can be found at https://sourceforge.net/p/lr2rmats/wiki/Home/
    Downloads: 0 This Week
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  • 13
    DockoMatic is a GUI application that is intended to ease and automate the creation and management of AutoDock jobs for high throughput screening of ligand/receptor interactions.
    Downloads: 1 This Week
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  • 14

    ASSA

    MOVED TO https://github.com/vanya-antonov/assa

    THE DEVELOPMENT AND DISTRIBUTION OF THIS PROJECT HAVE BEEN MOVED TO GITHUB: https://github.com/vanya-antonov/assa
    Downloads: 0 This Week
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  • 15
    CABBaGe

    CABBaGe

    Classification Algorithm Based on a Bayesian method for Genomics

    Downloads: 0 This Week
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  • 16
    aXonica

    aXonica

    An installation package for freeware bioimaging tools

    Download link: https://www.dropbox.com/s/jelbrho05m7yg8y/NeuroX_v.1.0.zip?dl=0 For Instructions Manual see Download section.
    Downloads: 0 This Week
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  • 17

    Panacea

    PAN And Core-gEnome Analysis

    A tool to calculate the Pan-Genome of a set of annotated genomes
    Downloads: 0 This Week
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  • 18
    SiBELia

    SiBELia

    Synteny Block ExpLoration tool

    Sibelia: A comparative genomic tool: It assists biologists in analysing the genomic variations that correlate with pathogens, or the genomic changes that help microorganisms adapt in different environments. Sibelia will also be helpful for the evolutionary and genome rearrangement studies for multiple strains of microorganisms.
    Downloads: 0 This Week
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  • 19
    This site hosts the source code for C++ version of the Broker for SBW, NOM module, advanced simulation suite, analysis applications and model editors.
    Downloads: 2 This Week
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  • 20

    LOCUST

    Custom Sequence Locus Typer

    A Custom Sequence Locus Typer for Classifying Microbial Genotypic and Phenotypic Attributes. Publication: Brinkac LM, Beck E, Inman J, Venepally P, Fouts DE, Sutton G. LOCUST: A Custom Sequence Locus Typer for Classifying Microbial Isolates. Bioinformatics (Oxford, England). 2017 Jan 27; https://www.ncbi.nlm.nih.gov/pubmed/28130240
    Downloads: 0 This Week
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  • 21

    DualTranscriptDiscovery

    Transcript-discovery approach for gene feature delimitation by RNA-seq

    This project contains Python scripts usable for a dual transcript-discovery approach that improves the delimitation of gene features from RNA-seq data in the chicken model. Documentation: http://bio.biologists.org/content/biolopen/suppl/2018/01/17/bio.028498.DC1/BIO028498supp.pdf Citation: Orgeur M., Martens M., Börno S. T., Timmermann B., Duprez D. and Stricker S. (2018). A dual transcript-discovery approach to improve the delimitation of gene features from RNA-seq data in the...
    Downloads: 1 This Week
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  • 22
    ABC-SysBio implements likelihood free parameter inference and model selection in dynamical systems. It is designed to work with both stochastic and deterministic models written in Systems Biology Markup Language (SBML).
    Downloads: 0 This Week
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  • 23

    scalpel

    Genetic variants discovery tool

    Bioinformatics pipeline for discovery of genetic variants from NGS reads.
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    Downloads: 9 This Week
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  • 24
    jlibsedml
    A Java library to facilitate SED-ML support for systems biology applications to read, validate, edit, and write SED-ML documents in compliance with MIASE guidelines. Also contains modules to execute simulation tasks and produce outputs. This project also contains the SED-ED editor application for SED-ML.
    Downloads: 1 This Week
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  • 25
    fcGENE: Genotype  format converter

    fcGENE: Genotype format converter

    Format converting tool for genotype Data (e.g.PLINK-MACH,MACH-PLINK)

    Main application is twofold: first to convert genotype SNP data into formats of different imputation tools like PLINK MACH, IMPUTE, BEAGLE and BIMBBAM, second to transform imputed data into different file formats like PLINK, HAPLOVIEW, EIGENSOFT and SNPTEST. Readable file formats: plink-pedigree (ped and map), plink-raw, plink-dosage, mach , minimac, impute, snptest, beagle and bimbam. Similarly all kinds of imputation of outputs are also accepted. Formats which can be generated by...
    Downloads: 2 This Week
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