CometZ is a simple side scrolling space shooter
To create an open source and openly developed mmorpg
Super Mario Python Final
Python/Pygame Game-Building Framework
Tactical, turn-based game engine, that uses OpenGL and WinAPI
Beyond dreams is a 3d solo/mmorpg game currently in developement.
Open source, moddable game engine for the "Polygon Love 2" game
Open Source Virtual World and MMOG Development Platform
Python Killboard Platform for EVE Online
Soundtrack editor for Guild Wars 2
Invaders like game, written in Python with Curses... :)