Showing 38 open source projects for "gene"

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  • 1
    nichenetr

    nichenetr

    NicheNet: predict active ligand-target links between interacting cells

    ...NicheNet prioritizes ligands according to their activity (i.e., how well they predict observed changes in gene expression in the receiver cell) and looks for affected targets with high potential to be regulated by these prioritized ligands.
    Downloads: 2 This Week
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  • 2
    clusterProfiler

    clusterProfiler

    A universal enrichment tool for interpreting omics data

    clusterProfiler is an R/Bioconductor package that provides a unified workflow for functional enrichment analysis to interpret high-throughput omics results. It supports both over-representation analysis and gene set enrichment analysis, letting you work with unranked gene lists or ranked statistics from differential pipelines. The package connects to multiple knowledge bases—such as Gene Ontology, KEGG, Reactome, Disease Ontology, MeSH and others—through a consistent interface so you can query different biological lenses without rewriting code. ...
    Downloads: 0 This Week
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  • 3
    Circuitscape.jl

    Circuitscape.jl

    Algorithms from circuit theory to predict connectivity

    Circuitscape is an open-source program that uses circuit theory to model connectivity in heterogeneous landscapes. Its most common applications include modeling the movement and gene flow of plants and animals, as well as identifying areas important for connectivity conservation. The new Circuitscape is built entirely in the Julia language, a new programming language for technical computing. Julia is built from the ground up to be fast. As such, this offers a number of advantages over the previous version.
    Downloads: 0 This Week
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  • 4
    JuiceFS

    JuiceFS

    JuiceFS is a distributed POSIX file system built on top of Redis

    ...Whether it's a public cloud, private cloud, or hybrid cloud, JuiceFS is available on any cloud of your choice and delivers flexibility, availability, scalability and strong consistency for your data-intensive applications. Purposely built to serve big data scenarios such as self-driving model training, recommendation engine, and Next-generation Gene Sequencing, JuiceFS specializes in high performance and easier management of tens of billion of files management. We bring JuiceFS to developers with the hope that it will be easy to use, reliable, high-performance, and solve all your file storage problems in a cloud environment.
    Downloads: 1 This Week
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  • 5
    scArches

    scArches

    Reference mapping for single-cell genomics

    Single-cell architecture surgery (scArches) is a package for reference-based analysis of single-cell data. scArches allows your single-cell query data to be analyzed by integrating it into a reference atlas. By mapping your data into an integrated reference you can transfer cell-type annotation from reference to query, identify disease states by mapping to healthy atlas, and advanced applications such as imputing missing data modalities or spatial locations.
    Downloads: 0 This Week
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  • 6
    The OpenGEREA is a open enrichment analysis framework for gene expression regulation data analysis.
    Downloads: 0 This Week
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  • 7

    SplitFusion

    Detection of gene fusion based on split alignments

    SplitFusion is a companion data pipeline for AMP, for the detection of gene fusion based on split alignments, i.e. reads crossing fusion breakpoints, with the ability to accurately infer in-frame or out-of-frame of fusion partners of a given fusion candidate. SplitFusion also outputs example breakpoint-supporting seqeunces in FASTA format, allowing for further investigations.
    Downloads: 0 This Week
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  • 8
    Grinn

    Grinn

    graph database and R package for omic data integration

    http://kwanjeeraw.github.io/grinn/
    Downloads: 0 This Week
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  • 9
    Clustergrammer

    Clustergrammer

    An interactive heatmap visualization built using D3.js

    ...Clustergrammer produces highly interactive visualizations that enable intuitive exploration of high-dimensional data and has several biology-specific features (e.g. enrichment analysis, see Biology-Specific Features) to facilitate the exploration of gene-level biological data.
    Downloads: 1 This Week
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  • 10

    MOIRAI

    Simple Scientific Workflow System for CAGE Analysis

    Cap analysis of gene expression (CAGE) is a sequencing based technology to capture the 5’ ends of RNAs in a biological sample. After mapping, a CAGE peak on the genome indicates the position of an active transcriptional start site (TSS) and the number of reads correspond to its expression level. CAGE is prominently used in both the FANTOM and ENCODE project.
    Downloads: 0 This Week
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  • 11

    CorNetMap

    A tool for Gene Expression Correlation Network

    Capabilities of CorNetMap: 1. Read data as tab-delimited text file. Can be used for analysis of any data set beyond gene expression. 2. Capable of both two-dimensional and multidimensional data analysis. 3. Calculate Pearson correlation and cross-correlation for analysis data with phase difference. 4. Generate correlation Heat-map and draws network map. 5. Save correlation data as text file. How to use and doccumentation: https://sourceforge.net/projects/cornetmap/files/Documentation_corNetMap.pdf Sample data for testing: https://sourceforge.net/projects/cornetmap/files/Test%20Data/ Citation: Cite CornetMap as " Khaund, A. ...
    Downloads: 0 This Week
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  • 12
    Zika-RNAseq-Pipeline

    Zika-RNAseq-Pipeline

    An open RNA-Seq data analysis pipeline tutorial

    RNA-seq analysis is becoming a standard method for global gene expression profiling. However, open and standard pipelines to perform RNA-seq analysis by non-experts remain challenging due to the large size of the raw data files and the hardware requirements for running the alignment step. Here we introduce a reproducible open source RNA-seq pipeline delivered as an IPython notebook and a Docker image.
    Downloads: 0 This Week
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  • 13
    Mauve computes and interactively visualizes genome sequence comparisons. Using FastA or GenBank sequence data, Mauve constructs multiple genome alignments that identify large-scale rearrangement, gene gain, gene loss, indels, and nucleotide substutit
    Downloads: 0 This Week
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  • 14
    A Tool for Retrieval, Visualization and Analysis of biological Pathways. Import a Gene or Protein Set from any Excel file. Automatically find signaling Pathways from KEGG. Integrate your Data in Seconds with a live interactive Force-directed Layout.
    Downloads: 0 This Week
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  • 15

    oasis-genomics

    Oasis Genomics cancer omics integration portal

    OASIS is an application that enables complex analytical queries across somatic mutations; copy number changes (CNV); and gene expression data. OASIS has been built on top of the BIoMart frameworks and has been extended to incorporate unique tools and visualizations to facilitate analysis of complex cancer "Omics" datasets.
    Downloads: 0 This Week
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  • 16

    PRADA

    PRADA : Pipeline for RNA-Sequencing Data Analysis

    Massively parallel sequencing of cDNA reverse transcribed from RNA (RNASeq) provides an accurate estimate of the quantity and composition of mRNAs. To characterize the transcriptome through the analysis of RNA-seq data, we developed PRADA. PRADA focuses on the processing and analysis of gene expression estimates, supervised and unsupervised gene fusion identification, and supervised intragenic deletion identification. PRADA currently supports 7 modules to process and identify abnormalities from RNAseq data: preprocess: Generates aligned and recalibrated BAM files. expression: Generates gene expression (RPKM) and quality metrics. ...
    Downloads: 1 This Week
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  • 17

    HomSI

    Homozygous Stretch Identifier from next-generation sequencing data

    ...Homozygosity mapping is based on this observation and several recessive disease genes have been discovered with the help of this technique in consanguineous families. The researchers typically use SNP arrays to determine the homozygous regions and then search for the disease gene by sequencing the genes within this candidate disease loci. Recently, the advent of next generation sequencing enables the concurrent identification of homozygous regions and the detection of mutations relevant for diagnosis, using data from a single sequencing experiment. In this respect, we have developed a novel tool that identifies homozygous regions using deep sequence data. ...
    Downloads: 0 This Week
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  • 18
    TOPS_CeMM

    TOPS_CeMM

    User Friendly Data Analysis Tool for Interaction Data

    TOPS provides the benchtop scientist with a free toolset to analyze, filter and visualize data from functional genomic gene-gene and gene-drug interaction screens with a flexible interface to accommodate various different technologies and analysis algorithms in addition to those already provided here.
    Downloads: 0 This Week
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  • 19

    locusvu

    Tool for genomics;automates data retrieval from db;enables workflows

    LocusVu is a novel Java based software tool that accepts a list of genomic loci (positions on the chromosome) as input and automates fetching of related information (cytogenetic band, gene name, OMIM data etc.) from public databases such as the UCSC genome browser database. It then enables multiple workflows on the retrieved results, like comparing multiple datasets (comparative genomics), viewing neighboring genes for a loci from within the tool itself, or graphically representing these results in bar / pie charts. ...
    Downloads: 0 This Week
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  • 20
    AMDA
    Automated Microarray Data Analysis
    Downloads: 2 This Week
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  • 21
    This plugin allow to visualize several e.g. gene expression values simultanously using pie charts. * Please cite http://www.biomedcentral.com/1752-0509/4/164 *
    Downloads: 1 This Week
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  • 22

    AntiSensePolyAFinder

    A antisense polyA search tool for SAPAS data analysis

    To find more details about the correlation level between sense and antisense transcripts to depend on gene expression levels, we used our SAPAS data to develop a method to analyze antisense polyA.
    Downloads: 0 This Week
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  • 23

    NGS data quality evaluation

    Python tool to evaluate the quality of high-throughput sequencing data

    ...Unlike other tools that analyze raw data, this is designed to evaluate the quality of the processed reads after mapping to a reference genome. The evaluation is performed in a genomic region defined by the user, and it provides some statistics computed from the reads that map to that region (ie. a single gene). The program provides a graphical output embedded in an html file. The analysis contains the sequencing quality along the reads, the mapping quality distribution, the coverage of the defined region, the overall quality at each nucleotide position, and the distribution of the coverage as a function of the GC content in the reference genome. ...
    Downloads: 0 This Week
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  • 24
    PAICE is a rapid bioinformatics pathway visualization tool for KEGG-compatible accessions derived from Illumina Solexa next-gen and Affymetrix datasets. It colors KEGG pathways while appreciating detection-calls and duplicate gene copies.
    Downloads: 0 This Week
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  • 25
    BIL++
    BIL++ is a set of standalone C++ packages for data processing in Bioinformatics (Graph mining, Bayesian networks, Genetic algorithm, Discretization, Gene expression data analysis, Hypothesis testing).
    Downloads: 0 This Week
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