Showing 113 open source projects for "high"

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  • 1
    BioNeMo

    BioNeMo

    BioNeMo Framework: For building and adapting AI models

    BioNeMo is an AI-powered framework developed by NVIDIA for protein and molecular generation using deep learning models. It provides researchers and developers with tools to design, analyze, and optimize biological molecules, aiding in drug discovery and synthetic biology applications.
    Downloads: 2 This Week
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  • 2
    kallisto

    kallisto

    Near-optimal RNA-Seq quantification

    kallisto is a program for near-optimal quantification of transcript abundances from RNA-Seq data, or more generally of target sequences using high-throughput sequencing reads. It is based on the idea of using pseudoalignment to quickly determine reads and targets’ compatibility, with no need for alignment. According to benchmarks done on a Mac desktop computer, kallisto can quantify 30 million human bulk RNA-seq reads in less than 3 minutes with just the read sequences and a transcriptome index, that in itself can take more than 10 minutes to build. ...
    Downloads: 5 This Week
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  • 3

    BBMap

    BBMap short read aligner, and other bioinformatic tools.

    ...BBMap: Short read aligner for DNA and RNA-seq data. Capable of handling arbitrarily large genomes with millions of scaffolds. Handles Illumina, PacBio, 454, and other reads; very high sensitivity and tolerant of errors and numerous large indels. Very fast. BBNorm: Kmer-based error-correction and normalization tool. Dedupe: Simplifies assemblies by removing duplicate or contained subsequences that share a target percent identity. Reformat: Reformats reads between fasta/fastq/scarf/fasta+qual/sam, interleaved/paired, and ASCII-33/64, at over 500 MB/s. ...
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    Downloads: 578 This Week
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  • 4
    PANDA

    PANDA

    A comprehensive and flexible quantification tool for proteomics data

    PANDA is a comprehensive and flexib tool for quantitative proteomics data analysis, which is developed based on our solid foundations in quantitative proteomics for years. Several novelties have been implemented in it. First, we implement the advantage algorithms of LFQuant (Proteomics 2012, 12, (23-24), 3475-84) and SILVER (Bioinformatics 2014, 30, (4), 586-7) into PANDA. Second, we consider the state-of-art concept of quantification reliability in this quantitative workflow. On the levels...
    Downloads: 0 This Week
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  • 5
    PDPBioGen

    PDPBioGen

    NOTICE OF CONSOLIDATION & PARTNERSHIP PENDING As of April 2026, the 20

    NOTICE OF CONSOLIDATION & PARTNERSHIP PENDING As of April 2026, the 20 pipelines of the QCAUS/PDPBioGen suites are undergoing consolidation for high-scale institutional research. Core 'Ford 2026' algorithms remain the proprietary IP of the Ford Peace and Justice Foundation. Academic users at partner institutions are currently performing validation; all other commercial inquiries must contact the author
    Downloads: 1 This Week
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  • 6
    CyberUnits

    CyberUnits

    Class library for computational cybernetics

    CyberUnits is a cross-platform class library for rapid development of high-performance computer simulations in life sciences. It supports modelling for biomedical cybernetics and systems biology with Object Pascal.
    Downloads: 6 This Week
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  • 7
    NGSEP

    NGSEP

    NGSEP (Next Generation Sequencing Experience Platform)

    NGSEP is an integrated framework for analysis of short and long DNA high throughput sequencing reads. The current version provides functionalities for both de-novo and reference guided analysis of sequencing data, including genome assembly, read mapping, variants detection and genotyping and de-novo analysis of data generated from reduced representation protocols. NGSEP also provides modules for analysis of genomic variation databases (VCF files), including functional annotation, filtering, format conversion, comparison, clustering, imputation, introgression analysis and different kinds of statistics. ...
    Downloads: 4 This Week
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  • 8
    OligoYap Portable

    OligoYap Portable

    Oligo design and bioinformatic analysis software.

    ...It works on windows8.1 and earlier operating systems, but has not been tried on windows10 and later. For better images, you can right-click the exe file and check the features/compatibility "Disable screen scaling in high DPI settings" box. On some systems (as win8.1) you may also need to check the "run as administrator" option. You can download the Turkish version (OligoYap_tur_portable.exe) from the Project Activity or by clicking on the Files menu. You can download the user manual video (OligoYap_eng_video.avi) from the Project Activity (click See All Activity) or by clicking on the Files menu.
    Downloads: 2 This Week
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  • 9

    EvidentialGene

    Evidence Directed Gene Construction for Eukaryotes

    EvidentialGene is a genome informatics project, "Evidence Directed Gene Construction for Eukaryotes", to construct high quality, accurate gene sets for animals and plants, developed by Don Gilbert at Indiana University, see http://arthropods.eugenes.org/EvidentialGene/ Construction refers to the combination of classical gene prediction, and more recent gene assembly (de-novo and genome-assisted) methods. The basic Evigene methods involve using available best-of-breed gene prediction and assembly software, combining all evidence for genes, from expressed sequences, genome assembly sequences, related species protein sequences, and any other, to annotate and score gene constructions. ...
    Downloads: 1 This Week
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  • 10
    CodonU

    CodonU

    A python project for analysis of codon usage for gene or genome analys

    With CodonU, you can now easily read, manipulate, and analyze various file formats used in this kind of analysis, and generate high-quality graphics suitable for publishing. This open-source project incorporates various statistical measures necessary for codon usage analysis, including codon adaptation index, codon bias index, Gravy score, and correspondence analysis for both nucleotide and protein sequences. Start using CodonU today and see how it can revolutionize your genomics research! ...
    Downloads: 0 This Week
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  • 11

    GenForm

    Generation of molecular formulas by high-resolution MS and MS/MS data

    This is an open source implementation of molecular formula calculation by high resolution MS and MS/MS data as described in M. Meringer, S. Reinker, J. Zhang, A. Muller: MS/MS Data Improves Automated Determination of Molecular Formulas by Mass Spectrometry. MATCH Commun. Math. Comput. Chem. 65, 259-290, 2011. The software user manual is available here: https://www.researchgate.net/publication/307964728_MOLGEN-MSMS_Software_User_Manual Example MS and MS/MS data files for GenForm can be downloaded here: https://sourceforge.net/p/genform/code/HEAD/tree/trunk/data/ A first program call could look like this: GenForm ms=SinapinicAcidMs.txt msms=SinapinicAcidMsMs.txt exist out
    Downloads: 3 This Week
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  • 12
    sRNAWorkbench

    sRNAWorkbench

    The UEA sRNA Workbench

    ...Including expression profiling of known mirco RNA (miRNA), identification of novel miRNA in deep-sequencing data and identification of other interesting landmarks within high-throughput genetic data
    Downloads: 16 This Week
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  • 13

    MAGeCK

    Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout

    Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout (MAGeCK) is a computational tool to identify important genes from the recent genome-scale CRISPR-Cas9 knockout screens technology. For instructions and documentations, please refer to the wiki page. MAGeCK is developed by Wei Li and Han Xu from Dr. Xiaole Shirley Liu's lab at Dana-Farber Cancer Institute/Harvard School of Public Health, and is maintained by Wei Li lab at Children's National Medical Center. We thank the support...
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    Downloads: 78 This Week
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  • 14
    hr ("High Resolution") is a small command-line utility to calculate possible elemental compositions for a given mass. It allows to run calculations interactively, in batch mode, via the command line, or (using a webserver) via a web interface.
    Downloads: 0 This Week
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  • 15

    slimfastq

    An efficient lossless compression for fastq files.

    slimfastq is a cli application that compresses/decompresses fastq files. It features: * High compression ratio * Relatively low cpu/memory usage * Truly lossless compression/decompression
    Downloads: 0 This Week
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  • 16

    MToolBox

    A bioinformatics pipeline to analyze mtDNA from NGS data

    MToolBox is a highly automated bioinformatics pipeline to reconstruct and analyze human mitochondrial DNA from high throughput sequencing data. MToolBox includes an updated computational strategy to assemble mitochondrial genomes from Whole Exome and/or Genome Sequencing (PMID: 22669646) and an improved fragment-classify tool (PMID:22139932) for haplogroup assignment, functional and prioritization analysis of mitochondrial variants. MToolBox provides pathogenicity scores, profiles of genome variability and disease-associations for mitochondrial variants. ...
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    Downloads: 12 This Week
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  • 17
    gsasnp2

    gsasnp2

    PubMed ID: 29562348 / DOI: 10.1093/nar/gky175

    * GSA-SNP2 is a successor of GSA-SNP (Nam et al. 2010, NAR web server issue). GSA-SNP2 accepts human GWAS summary data (rs numbers, p-values) or gene-wise p-values and outputs pathway genesets ‘enriched’ with genes associated with the given phenotype. It also provides both local and global protein interaction networks in the associated pathways. * Article: SYoon, HCTNguyen, YJYoo, JKim, BBaik, SKim, JKim, SKim, DNam, "Efficient pathway enrichment and network analysis of GWAS summary data...
    Downloads: 5 This Week
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  • 18
    CBMPy

    CBMPy

    PySCeS Constraint Based Modelling

    ...CBMPy supports user interaction via: - interactive console or as a library for advanced use - GUI, visual representation of the model, analysis methods - a SOAP based webAPI exposes high level functionality via web services
    Downloads: 0 This Week
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  • 19
    proTRAC

    proTRAC

    Use proTRAC to annotate genomic piRNA clusters

    proTRAC detects genomic piRNA clusters. It considers all the relevant features of mapped sequence reads like the amount of 1U/10A, size and strand bias to ensure a high specificity.
    Downloads: 1 This Week
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  • 20
    De_Lux

    De_Lux

    Deconvolution of luminescence cross-talk in microplate reader data

    An algorithm to deconvolve the luminescence cross-talk in high-throughput gene expression profiling to recover the true luminescence activity of a microplate.
    Downloads: 0 This Week
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  • 21

    Root Phenotyping Suite

    Three different software tools for phenotyping plant root images

    RootAnalyzer is a fully automated tool, for efficiently extracting and analyzing anatomical traits from root-cross section images. RootAnalyzer segments the plant root from the image's background, classifies and characterizes the cortex, stele, endodermis and metaxylem, and produces statistics about the morphological properties of the root cells and tissues. RTipC is a system for the fully automated detection and classification of root tips in root images obtained either by 2d flat bed...
    Downloads: 1 This Week
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  • 22
    High-Throughput Tabular Data Processor
    HIGH-THROUGHPUT TABULAR DATA PROCESSOR (HTDP) is Java application that is intended to facilitate data exploration and reduction tasks in large text files resulting from high throughput technologies, e.g. massively parallel sequencing or microarrays. The software has been optimized for microarray and deep parallel sequencing data, however it can accept any character delimited tabular data sets.
    Downloads: 0 This Week
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  • 23

    Pipebar

    A fast and accurate pipeline for DNA barcoding analysis.

    ...Here we proposed a pipeline for DNA chromatograms analysis of Sanger platform by open-source tools integration in order to reduce cost with standard commercial licences ensuring high quality, robustness with reduced time. Pipebar is a python application created to automatization of processing chromatogram trace files to high-quality DNA sequences for downstream analyses.
    Downloads: 0 This Week
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  • 24
    HCS Analyzer

    HCS Analyzer

    High Content Screening Analyzer

    HCS Analyzer is an open source software dedicated to High Content Screening data processing and analysis.
    Downloads: 0 This Week
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  • 25
    DockoMatic is a GUI application that is intended to ease and automate the creation and management of AutoDock jobs for high throughput screening of ligand/receptor interactions.
    Downloads: 0 This Week
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