Search Results for "fusioncatcher"

...Furthermore, fusion detection tools tend to report many false positives. Therefore, we developed a detection and filtering workflow bundled into a Singularity container for a streamlined and easy-to-use application. Arriba and FusionCatcher are utilized for fusion calling. Our filtering pipeline uses read counts generated by FeatureCounts and insert size estimation by Picard Tools for calculation of our filtering metrics: Fusion Transcript Score (FTS). Further filtering is realized by a custom blacklist, our Promiscuity Score (PS) and Robustness Score (RS). Identified fusion genes are reported with evidence levels based on our filtering. ...

FusionCatcher searches for novel/known somatic fusion genes, translocations, and chimeras in RNA-seq data (paired-end reads from Illumina NGS platforms like Solexa and HiSeq) from diseased samples. The aims of FusionCatcher are: - very good detection rate for finding candidate fusion genes, - very easy to use (i.e. no a priori knowledge of databases and bioinformatics is needed in order to run FusionCatcher), - very good detection of challenging fusion genes, like for example IGH fusions, CIC fusions, DUX4 fusions, CRLF2 fusions, TCF3 fusions, etc...

fusion_test.sh is a shell script to detect fusion in DNAseq or RNAseq. It uses chimerascan, SOAPfuse, MapSplice2, FusionMap, fusioncatcher, TopHat and EricScript. The output files of chimerascan are further annotated by Jinja and Pegasus Fusion. ***Updated*** Note: EricScript uses old version of Samtools. Download the modified program and Samtools-0.1.19 here. An error in the configuration for fusioncathcer is corrected. FusionMap has been deprecated. It is changed to Oshell. ...