DownloadThis is the protein similarity network - PSIN. Here, the nodes are human proteins and they are linked only if they share considerable sequence similarity.
We found that this network is particularly useful to distinguish approved from problematic drug-targets.
Here you also find the complete set of programs and datasets we used for this purpose.
Free to help further test and develop this project. Your help and expertise are much appreciated !
If you have any questions, please do not hesitate to contact us in the forum or by email.
Please see the original manuscript:
Lopes, TJS, et al. (2015) - "Identifying problematic drugs based on the characteristics of their targets" - Frontiers in Pharmacology doi: 10.3389/fphar.2015.00186
License
GNU General Public License version 3.0 (GPLv3), Creative Commons Attribution ShareAlike License V3.0Follow The Protein Similarity Network
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