This is the protein similarity network - PSIN. Here, the nodes are human proteins and they are linked only if they share considerable sequence similarity.
We found that this network is particularly useful to distinguish approved from problematic drug-targets.
Here you also find the complete set of programs and datasets we used for this purpose.
Free to help further test and develop this project. Your help and expertise are much appreciated !
** THE CODE AND THE DATABASE FILES WILL COME SOON.
** THE MANUSCRIPT IS NOW UNDER REVIEW.
If you have any questions, please do not hesitate to contact us in the forum or by email.
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