Mutascope is a software suite designed to analyze data from high throughput sequencing of PCR amplicons, with an emphasis on normal-tumor comparison for the accurate and sensitive identification of low prevalence mutations.

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Direct PCR amplicon sequencing differs from fragment shotgun DNA sequencing. Mutascope leverages the specific read distribution and alignment to incase accuracy for calling variants at low allelic fraction in tumor-normal pair comparison

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2013-01-24
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