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VarScan

Variant detection in next-generation sequencing data

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Download VarScan.v2.3.5.jar
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Description

Variant detection in massively parallel sequencing. For one sample, calls SNPs, indels, and consensus genotypes. For tumor-normal pairs, further classifies each variant as Germline, Somatic, or LOH, and also detects somatic copy number changes.

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Features

  • Calls SNPs and Indels from SAMtools pileup files
  • Filters variants by coverage, read depth, variant frequency, and base quality
  • Determines somatic status (Somatic, Germline, LOH) for Tumor-Normal pairs
  • Compares, merges, and intersects two lists of variants
  • Limits variant calls to a set of target positions or target regions
  • Free for non-commercial use.

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User Ratings

 
 
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User Reviews

  • Posted by MarcoWray 2013-06-06

    Very useful. Thanks.

  • Posted by Cayden 2012-10-31

    excellent app

  • Posted by Samuel 2012-03-26

    works great.

  • Posted by Dan Koboldt 2010-01-22

    We use VarScan at the Genome Center at Washington University to call variants in Roche/454 and Illumina/Solexa data.

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Additional Project Details

Intended Audience

Science/Research

User Interface

Command-line

Programming Language

Java

Registered

2010-01-13

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