Re: [Obo-discuss] Relation that corresponds to GO annotations

[Chris M. <CJM...@lb...>]

On Oct 26, 2010, at 4:31 PM, Alan Ruttenberg wrote:

>> [7] some instance of p53 *is part of* some instance of TF complex [GO
>> CC]
>> [8] some instance of p53 *participates_in* some instance of damaged
>> DNA binding [GO MF]
>
> This one is contentious. There are differences in opinion between
> considering the MFs functions (which, for instance, I adhere to) and
> considering them processes (which Chris apparently adheres to).
>
> In any case the pattern doesn't work in all cases, e.g.
> http://amigo.geneontology.org/cgi-bin/amigo/term-details.cgi?term=GO:0017056
> The action of a molecule that contributes to the structural integrity
> of the nuclear pore complex.

It's likely that terms such as this will be obsoleted, it doesn't tell  
you anything a nuclear pore annotation doesn't.

> These need further thought.
>
> I made a few slides about this once - see
> http://ashby.csail.mit.edu/presentations/Interontology08.ppt slides
> 40-43
>
> -Alan
>
>> [9] some instance of p53 *participates_in* some instance of apoptosis
>> [GO BP]
>
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