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[Obo-phenotype-commits] obo/ontology/phenotype mammalian_phenotype.obo, 1.265, 1.266 mosquito_insecticide_resistance.obo, 1.486, 1.487
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From: Seth C. <sjc...@us...> - 2009-06-19 07:03:20
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Update of /cvsroot/obo/obo/ontology/phenotype In directory 23jxhf1.ch3.sourceforge.com:/tmp/cvs-serv10950/phenotype Modified Files: mammalian_phenotype.obo mosquito_insecticide_resistance.obo Log Message: Automated file update Index: mammalian_phenotype.obo =================================================================== RCS file: /cvsroot/obo/obo/ontology/phenotype/mammalian_phenotype.obo,v retrieving revision 1.265 retrieving revision 1.266 diff -C2 -d -r1.265 -r1.266 *** mammalian_phenotype.obo 9 Jun 2009 07:03:33 -0000 1.265 --- mammalian_phenotype.obo 19 Jun 2009 07:03:15 -0000 1.266 *************** *** 1,4 **** format-version: 1.2 ! date: 08:06:2009 16:07 saved-by: csmith auto-generated-by: OBO-Edit 1.101 --- 1,4 ---- format-version: 1.2 ! date: 18:06:2009 15:40 saved-by: csmith auto-generated-by: OBO-Edit 1.101 *************** *** 39878,39882 **** name: testis tumor def: "presence of abnormal rapidly proliferating cells in the testis, usually in the form of a distinct mass" [J:60034, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] ! is_a: MP:0002020 ! increased tumor incidence [Term] --- 39878,39882 ---- name: testis tumor def: "presence of abnormal rapidly proliferating cells in the testis, usually in the form of a distinct mass" [J:60034, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] ! is_a: MP:0009590 ! gonad tumor [Term] *************** *** 41085,41089 **** def: "presence of abnormal rapidly proliferating cells in the ovary, usually in the form of a distinct mass" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] synonym: "ovarian tumor" EXACT [] ! is_a: MP:0002020 ! increased tumor incidence [Term] --- 41085,41089 ---- def: "presence of abnormal rapidly proliferating cells in the ovary, usually in the form of a distinct mass" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] synonym: "ovarian tumor" EXACT [] ! is_a: MP:0009590 ! gonad tumor [Term] *************** *** 54745,54749 **** id: MP:0009587 name: abnormal plasma membrane sphingolipid content ! def: "altered amounts of the phospholipids\nfound especially in, but not limited to, the cell membrane of nerve tissue\nthat yield sphingosine, choline, a fatty acid, and phosphoric acid upon\nhydrolysis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] is_a: MP:0003950 ! abnormal plasma membrane morphology --- 54745,54749 ---- id: MP:0009587 name: abnormal plasma membrane sphingolipid content ! def: "altered amounts of the phospholipids found especially in, but not limited to, the cell membrane of nerve tissue that yield sphingosine, choline, a fatty acid, and phosphoric acid upon hydrolysis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] is_a: MP:0003950 ! abnormal plasma membrane morphology *************** *** 54751,54755 **** id: MP:0009588 name: increased plasma membrane sphingolipid content ! def: "abnormal accumulation of\nthe phospolipids found especially in, but not limited to, the cell membrane\nof nerve tissue that yield sphingosine, choline, a fatty acid, and\nphosphoric acid upon hydrolysis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] is_a: MP:0009587 ! abnormal plasma membrane sphingolipid content --- 54751,54755 ---- id: MP:0009588 name: increased plasma membrane sphingolipid content ! def: "abnormal accumulation of the phospolipids found especially in, but not limited to, the cell membrane of nerve tissue that yield sphingosine, choline, a fatty acid, and phosphoric acid upon hydrolysis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] is_a: MP:0009587 ! abnormal plasma membrane sphingolipid content *************** *** 54760,54763 **** --- 54760,54826 ---- is_a: MP:0009587 ! abnormal plasma membrane sphingolipid content + [Term] + id: MP:0009590 + name: gonad tumor + def: "presence of abnormal rapidly proliferating cells in the testis or ovary, usually in the form of a distinct mass" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + is_a: MP:0002020 ! increased tumor incidence + + [Term] + id: MP:0009591 + name: liver adenocarcinoma + def: "malignant neoplasm of epithelial cells in the liver" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + synonym: "hepatic adenocarcinoma" EXACT [] + is_a: MP:0008019 ! liver tumor + is_a: MP:0009308 ! adenocarcinoma + + [Term] + id: MP:0009592 + name: Leydig cell tumor + def: "rare testicular tumors of the male gonadal interstitium that are frequently hormonally active, leading to feminizing or virilizing syndromes; Leydig cell tumors comprise 1-3% of all testicular neoplasms, can be pure or mixed with other sex cord-stromal or germ cell tumors, and are usually benign, although malignant variants also occur" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + synonym: "interstitial cell tumor of testis" EXACT [] + is_a: MP:0006262 ! testis tumor + + [Term] + id: MP:0009593 + name: absent chorion + def: "absence of the outermost extraembryonic membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + synonym: "absent membrana serosa" EXACT [] + is_a: MP:0002836 ! abnormal chorion morphology + + [Term] + id: MP:0009594 + name: abnormal corneocyte envelope morphology + def: "any structural or developmental anomaly of the electron-dense layer of highly transglutaminase cross-linked protein that is deposited on the inner surface of the plasma membrane of corneocytes in the outermost layers of the epidermis; a monomolecular layer of ceramides is covalently attached to the outer surface of the CE to form a hydrophobic lipid envelope that covers each corneocyte and provides continuity with the lipid matrix" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + synonym: "abnormal cornified envelope morphology" EXACT [] + synonym: "abnormal subplasmalemmal dense zone" EXACT [] + is_a: MP:0001240 ! abnormal cornified layer morphology + + [Term] + id: MP:0009595 + name: enlarged corneocyte envelope + def: "increased size of the electron-dense layer of highly transglutaminase cross-linked protein that is deposited on the inner surface of the plasma membrane of corneocytes in the outermost layers of the epidermis" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + synonym: "enlarged cornified envelope" EXACT [] + synonym: "enlarged subplasmalemmal dense zone" EXACT [] + is_a: MP:0009594 ! abnormal corneocyte envelope morphology + + [Term] + id: MP:0009596 + name: abnormal stratum corneum lipid matrix formation + def: "altered lipid composition or intercellular lipid matrix assembly in the stratum corneum, usually resulting in loss of epidermal barrier function; normally, the intercorneocyte lipid matrix consists of a complex lipid mixture of ceramides, cholesterol and long-chain saturated fatty acids that self-assembles into an ordered multilayer structure known as lipid lamellae" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + synonym: "abnormal intercorneocyte lamellar lipids" EXACT [] + synonym: "abnormal intercorneocyte lipid lamellae" EXACT [] + synonym: "abnormal stratum corneum extracellular lipid matrix" EXACT [] + synonym: "defective epidermal lipid matrix composition" EXACT [] + synonym: "epidermal lipid matrix defects" EXACT [] + is_a: MP:0001240 ! abnormal cornified layer morphology + + [Term] + id: MP:0009597 + name: impaired stratum corneum desquamation + def: "dysregulated shedding of the outermost layer of corneocytes, affecting the integrity and thickness of the stratum corneum; may result in xerotic and ichthyotic conditions" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] + synonym: "abnormal corneocyte desquamation" EXACT [] + synonym: "impaired corneocyte shedding" EXACT [] + is_a: MP:0001240 ! abnormal cornified layer morphology + [Typedef] id: part_of |