Activity for Varun Kothamachu

  • Varun Kothamachu Varun Kothamachu modified ticket #125

    Charge

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #125

    Dear Andreas, Thank you for the term request. I am weary to use "charge" to represent the definition that you are after. Instead, I have created a new term called "fractional occupancy" SBO:0000663. I hope this works for you.

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #124

    Hi Andreas, I have now created a new term SBO:0000662 in response to your request.

  • Varun Kothamachu Varun Kothamachu modified ticket #124

    Occupancy

  • Varun Kothamachu Varun Kothamachu modified ticket #123

    Capacity

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #123

    Dear Andreas, Thank you for the term request. I have created a new term SBO:0000661 in response.

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #121

    Hi Vasundra, I have created new terms for polymerisation (SBO:0000652) and de-polymerisation (SBO:0000653). For co-transport we now have the term SBO:0000654 which is currently described for 2 substances. I am not aware of examples of co-transport being used for more than 2 substances. Could you share some examples ? Will wait for more responses on the other terms.

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #121

    Posting on behalf of Vasundra: Hi Varun and Nicolas, Polymerization/Depolymerization looks good to me. Co-transport: "simultaneous transport of two substances" : isn't "two" a bit restrictive here? There could be more than two substances co-transported, right? Could we say "of two or more substances"? Regarding the term Transfers to, the definition in the paper was: "a chemical group is transferred from a high-energy donor to a recipient, forming a covalently bonded modification." So I don't think...

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #121

    Hi Nicolas, Vasundra, I have the following definitions and proposed changes for the terms that you both have been discussing. Kindly let me know if you have any feedback on the proposed definitions before I create the terms. I will create new terms 1. Polymerization (Parent term: SBO:0000182 - conversion) A chemical reaction involving two or more molecules combining to form a larger molecule with repeated structural units. 2. De-polymerization (Parent term: SBO:0000182 - conversion) A chemical reaction...

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #122

    Hi Nicolas, I agree on moving SBO:0000376 - hydrolysis as a child term to SBO:0000178 - cleavage. Have made this change and am now closing the ticket now.

  • Varun Kothamachu Varun Kothamachu modified ticket #122

    Make "hydrolysis" a child of "conversion"

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #124

    Proposed definitions are Preferred Name: Genome-scale model Definitions: A stoichiometric model of metabolism derived from information found in the genome and used to describe the metabolic potential of an organism. It is valuable for investigations on metabolic potential of an organism using constraint-based modelling approaches. subClassOf: domain model seeAlso: http://identifiers.org/pubmed/21993642 Preferred Name: Patient-derived genome-scale model Definitions: A stoichiometric model of metabolism...

  • Varun Kothamachu Varun Kothamachu modified ticket #124

    Terms for Genome-scale and Patient-derived genome scale models

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #124

    Proposed definitions are Preferred Name: Genome-scale model Definitions: A stoichiometric model of metabolism derived from information found in the genome and used to describe the metabolic potential of an organism. It is valuable for investigations on metabolic potential of an organism using constraint-based modelling approaches. subClassOf: domain model Preferred Name: Patient-derived genome-scale model Definitions: A stoichiometric model of metabolism generated using data (example: transcriptomic)...

  • Varun Kothamachu Varun Kothamachu created ticket #124

    Terms for Genome-scale and Patient-derived genome scale models

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #63

    SBO:0000492 - amplitude with a parent SBO:0000002 - quantitative systems description parameter was created.

  • Varun Kothamachu Varun Kothamachu modified ticket #79

    sbo terms for reaction rates

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #79

    Closing this ticket as it has been dealt with in ticket #105

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #79

    Closing this ticket as it has been dealt with in #105

  • Varun Kothamachu Varun Kothamachu modified ticket #83

    refining SBO:0000475 - "periodic light forcing function"

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #83

    ticket will be closed now due to no further comments or updates.

  • Varun Kothamachu Varun Kothamachu modified ticket #89

    transport reaction direction

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #89

    ticket will be closed now due to no further comments or updates.

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #95

    Ticket will be closed as there has been no further discussion or update to these terms.

  • Varun Kothamachu Varun Kothamachu modified ticket #95

    Sideproduct and sidesubstrate

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #95

    Ticket closed as there has been no further discussion or update to these terms.

  • Varun Kothamachu Varun Kothamachu modified ticket #96

    Reversible and irreversible reaction or process

  • Varun Kothamachu Varun Kothamachu modified ticket #96

    Reversible and irreversible reaction or process

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #96

    Created SBO:0000650 - reversible process and SBO:0000651 - irreversible process. Best, Varun

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #96

    Created terms SBO:0000650 - reversible process and SBO:0000651 - irreversible process. Best, Varun

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #96

    Created terms SBO:0000650 - reversible reaction and SBO:0000651 - irreversible reaction. Best, Varun

  • Varun Kothamachu Varun Kothamachu modified ticket #97

    Enzymatic catalysis

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #97

    Please have a look at the term for catalysis SBO:0000172. This can be useful for this purpose. Best, Varun

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #117

    SBO:0000641 created by Nick Juty.

  • Varun Kothamachu Varun Kothamachu modified ticket #100

    high and low affinity receptors

  • Varun Kothamachu Varun Kothamachu modified ticket #101

    dimer and homodimer

  • Varun Kothamachu Varun Kothamachu modified ticket #103

    Request for adding the term "growth rate" for parameter annotation

  • Varun Kothamachu Varun Kothamachu modified ticket #104

    Request for adding the term "effective catalytic enzyme rate" for parameter annotation

  • Varun Kothamachu Varun Kothamachu modified ticket #108

    Flux balance framework

  • Varun Kothamachu Varun Kothamachu modified ticket #109

    Destinguishing flux bound parameters

  • Varun Kothamachu Varun Kothamachu modified ticket #111

    pseudoreaction terms

  • Varun Kothamachu Varun Kothamachu modified ticket #114

    Request for DNA Region and RNA Region SBO Term

  • Varun Kothamachu Varun Kothamachu modified ticket #115

    SBO terms to facilitate SBML/BioPAX mappings

  • Varun Kothamachu Varun Kothamachu modified ticket #116

    SBOL participant (object) roles request

  • Varun Kothamachu Varun Kothamachu modified ticket #117

    pMg parameter

  • Varun Kothamachu Varun Kothamachu modified ticket #120

    Term request: biomass

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #120

    Dear Matthias, Thank you for your feedback via email. The term for biomass is now online and can be referred to using the id SBO:0000649. I will now close this ticket. Thank you for your support. Best, Varun

  • Varun Kothamachu Varun Kothamachu modified ticket #120

    Term request: biomass

  • Varun Kothamachu Varun Kothamachu modified ticket #120

    Term request: biomass

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #120

    Dear Matthias, Following our email conversation, we will be creating a new term for biomass under SBO:0000241. Kindly comment on the definition for the term that we are considering. biomass - A composite representation of material entities required for organismal growth. It includes macromolecular content (eg. cellular protein fraction), metabolic constitution of each fraction (eg. amino acids), and atomic composition (eg. nitrogen atoms). Varun

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #120

    Dear Matthias, Following our email conversation, we will be creating a new term for biomass under SBO:0000241. Before the term is madeKindly comment on the definition for the term that we are considering. biomass - A composite representation of material entities required for organismal growth. It includes macromolecular content (eg. cellular protein fraction), metabolic constitution of each fraction (eg. amino acids), and atomic composition (eg. nitrogen atoms). Varun

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #120

    Dear Matthias, Following our email conversation, we will be creating a new term for biomass under SBO:0000241. Kindly comment on the definition for the term that we are currently considering. biomass - A composite representation of material entities required for organismal growth. It includes macromolecular content (eg. cellular protein fraction), metabolic constitution of each fraction (eg. amino acids), and atomic composition (eg. nitrogen atoms). Varun

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #120

    Dear Matthias, Thank you for the term request. Why not use one of the terms under material entity (SBO:0000240) or functional entity (SBO:0000241) nodes for this ? Varun

  • Varun Kothamachu Varun Kothamachu modified ticket #120

    Term request: biomass

  • Varun Kothamachu Varun Kothamachu modified ticket #119

    Compound and enzyme molecular mass

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #119

    Dear Wolf, Thank you for your term request. I have now created two new terms SBO:0000647 and SBO:0000648. Regards, Varun P.S. Nick has recently completed his stint at EMBL-EBI and will no longer be curating SBO

  • Varun Kothamachu Varun Kothamachu modified ticket #119

    Compound and enzyme molecular mass

  • Varun Kothamachu Varun Kothamachu modified ticket #119

    Compound and enzyme molecular mass

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #118

    Mathml for this term has been updated and the bug has been fixed. You can now see...

  • Varun Kothamachu Varun Kothamachu modified ticket #118

    Add SBO for mass action rate law for reversible reactions, continuous scheme

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #117

    Term created by Nick Juty.

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #117

    Term created by Nick Juty.

  • Varun Kothamachu Varun Kothamachu modified a comment on ticket #117

    Term created by Nick Juty.

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #117

    Term created by Nick Juty

  • Varun Kothamachu Varun Kothamachu modified ticket #117

    pMg parameter

  • Varun Kothamachu Varun Kothamachu modified ticket #118

    Add SBO for mass action rate law for reversible reactions, continuous scheme

  • Varun Kothamachu Varun Kothamachu posted a comment on ticket #118

    Dear Stefan, As per your request, this term has now been created (SBO:0000646). We...

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