Thanks for the quick reply. I did try the repair steps, but they did not work.
I am in the process of recovering my computer after it failed, and these steps didn't work for me. There is no 'ProtectedUserKey.bin' file. As I understand it, I cannot open my KeePass database because on my current Windows installation, there is no ....users\Trish anymore. The error I get when trying to open my KeePass file is -- c:\users\Administrator\Documents\keepass\xxx.kdbx Failed to load the specified file! The file signature is invalid. Either the file iasn't a KeePass database file at all...