Hi Chris, David, Is is possible to get this done ASAP because my student needs to...
NTR: reduced folate transmembrane transport
NT: Intestinal folic acid absorption
Hi Leonore, Thanks for the document, it all makes sense. For the transcription factors,...
Hi Leonore, Was there an attachment? I can't seem to see it. Thanks, Rachael.
Hi Leonore, I have made a diagram for the plant miRNA biogenesis pathway (attached...
Hi David, "Maybe reposition as a child of 'primary miRNA methylation'?" I don't think...
NTR: "miRNA export from nucleus" and "miRNA transporter activity"
NTR: miRNA 2'-O-methylation
NTR: Thymidylate synthase inhibitor binding
NTR: folic acid receptor activity
Parentage of methotrexate binding
Hi David, There is no indication that they are talking about neuropores, so I think...
Possible NTR: anterior neural tube closure
Hi Leonore, OK, thanks. If you can send me what you can, I will try to work on the...
Hi Kimberly, Just to let you know this was dealt with in this SF ticket https://sourceforge.net/p/geneontology/ontology-requests/11638/...
Hi Leonore, Have you had chance to work on the plant miRNA section and figure? I...
Definition of 'deadenylation involved in gene silencing by miRNA'
Protein2GO report not working
Val, see https://sourceforge.net/p/geneontology/annotation-issues/1317/
Above list of annotations with curation groups identified; mRNA cleavage involved...
Hi David, Is the above proposed solution agreed now? I would like to update my guidelines...
It is (see screenshot) - am I missing something?
Hi David, Karen, I think I understand what you mean, just to confirm - you are saying...
Figure 1 Powerpoint file here
Hi Leonore, Thanks very much for putting together the annotations for the plant pathway....
Here is some feedback from Dmitry from MGI. My responses are prefixed with a 'RH>'....
Thanks for your reply Karen, I thought the removal of the part_of relation between...
Hi Leonore, Just to say thanks for this, I am going through this now so I'll send...
GO:0035068 micro-ribonucleoprotein complex parentage
I think the proposed solution looks OK. You would then have the major mechanisms...
Update on miPEP sequences: UniProt have now included the miPEP sequences from Lauressergues,...
Hi David, Would the simplest solution be to broaden the definition of mRNA processing...
I have made a decision tree to replace Table 2 in the guidelines (attached at the...
miRNA annotation guidelines
I have made a decision tree to replace Table 2 in the guidelines. Feel free to add...
Gene silencing definition too narrow.
Hi Kimberly, That's a good point, I hadn't looked closely at the parent. The gene...
Hi Tanya, I will take a look at converting the table into a decision tree. Thanks...
Hi Leonore, Firstly, thank you very much for reading the document and providing feedback....
Ensembl name lookup
miRNA annotation guidelines
Additional parent for mature miRNA 3'end processing
OK, thanks Val, that makes it clear. Then the new term I guess should be ³pre-miRNA...
Hi Val, I¹m not sure I get the distinction. Transmembrane transporter activity "Enables...
NTR: pre-miRNA transmembrane transporter activity
Missing parent for S-adenosylmethionine cycle
Parentage of GO:0000981
Update to GOrel to enable use of RNAcentral IDs in extensions
NTR: mRNA cleavage involved in gene silencing by siRNA
NTR: mRNA cleavage involved in gene silencing by siRNA
NTR: endoribonuclease activity, cleaving miRNA-paired mRNA
Query parentage of GO:0060969 neg. reg. gene silencing
Hi Paola, Thanks for this. Can you set my dbxrf the same as for Nancy Campbell and...
Hi Paola, I think your suggestion is good. Since the alternative pathway has only...
Hi Paola, This paper is quite recent http://www.ncbi.nlm.nih.gov/pubmed/?term=24837021....
Hi Paola, I guess it could be a sub-type, but it depends what GO:0006303 is describing....
NTR: DSB repair via alternative non homologous end joining
Taxon constraint:GO:0042574
Also GO:0005503 all-trans retinal binding has the same constraint.
Taxon constraint:GO:0042574
I would hope that Chris will bring this to an annotation call as we have already...
Hi, Wouldn't the correct way to annotate be to use a specific ECO term for the assay?...
UniProt annotations; P12979 appears to be involved in muscle atrophy normally. For...
SP_KW:KW-0346
Yes, good point, this term should only be used for electronic annotations when nothing...
Annot. to GO:0010421 hydrogen peroxide-mediated programmed
Ah, OK. I see the distinction - I was thinking of other organism as other species...
Bad E. coli annotations
Hi Jim, This annotation is not visible anymore, so your fix has worked. Rachael....
Hi Val, Can you tell us which gene this refers to? Rachael.
SP_KW:KW-0238 DNA binding
Keyword is still present only on these; P20433 Q8VC56 Q80XJ2 Sent to UniProt.
Sent to UniProt.
Hi Paola, I'm looking into this and it looks like the cell death is from the same...
Sent to UniProt
Only P04910 still has the DNA repair keyword. Sent to UniProt.
Sent to UniProt
SL-0455 should be removed from the following entries; O13729 pun1 O14014 rga3 O14248...
Duplicate of https://sourceforge.net/p/geneontology/annotation-issues/813/ However,...
SPKW mapping to protein folding UniProtKB-KW:KW-0697
problem mapping for glutamate--cysteine ligase regulatory s
This annotation has disappeared.
It seems that the is_a relation to iron ion binding was deleted in 2012. However,...
I can't see any PAINT annotations to this term, but there are manual annotations...
DPAGT1 is GO:0031227 or GO:0005789, not GO:0016021
I think Ruth was querying P05121, which now does not have the annotation from KW-0617....
Hi Val, We are not getting any GO annotations for pombe from this mapping anymore...
Reactome mapping to wrong yeast
Annotation has been removed.
O14012 incorrect annotation
I'm going to delete all the TAS annotations from this paper as it's a review. By...
I'm going to delete all the TAS annotations from this paper as it's a review. By...
PKA regulatory subunit maps to 'kinase activity' in spkw2go
Q6NW93 still has two GO annotations derived from KW-0418. Have submitted to the UniProt...
Both of these proteins now have manual annotations to this term. The yeast is IMP...
Sent to UniProt.
Hi Val, Is this still an issue? InterPro:IPR001719 doesn't have this mapping anymore...
E. coli NuoE annotated to mitochondrial complex
This annotation no longer exists.