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#11778 NTR: "miRNA export from nucleus" and "miRNA transporter activity"

BHF-UCL
closed-accepted
miRNA (10)
5
2015-06-29
2015-06-29
No

Is it possible to have two new terms for the plant miRNA biogenesis pathway;
1. "miRNA export from nucleus" as a child of GO:0006405 RNA export from nucleus
2. "miRNA transporter activity" as a child of GO:0005487 nucleocytoplasmic transporter activity

In animals it is the pre-miRNA that is exported from the nucleus (and we have the equivalent terms for this) but in plants the cleavage of pre-miRNA happens in the nucleus and the miRNA is exported by the Hasty protein.

References:
http://www.ncbi.nlm.nih.gov/pubmed/15738428/
http://www.genomebiology.com/2011/12/4/221

Please add GOC:BHF_miRNA and GOC:rph

Thanks,
Rachael.

Discussion

  • David Hill

    David Hill - 2015-06-29
    • assigned_to: David Hill
     
  • David Hill

    David Hill - 2015-06-29
    • status: open --> closed-accepted
     
  • David Hill

    David Hill - 2015-06-29

    [Term]
    +id: GO:0061716
    +name: miRNA export from nucleus
    +namespace: biological_process
    +def: "The directed movement of a processed miRNA from the nucleus to the cytoplasm." [GOC:BHF_miRNA, GOC:rph, PMID:15738428, PMID:21554756]
    +is_a: GO:0006405 ! RNA export from nucleus
    +created_by: dph
    +creation_date: 2015-06-29T08:54:41Z
    +
    +[Term]
    +id: GO:0061717
    +name: miRNA transporter activity
    +namespace: molecular_function
    +def: "Enables the directed movement of cleaved miRNAs between the nucleus and the cytoplasm of a cell." [GOC:BHF_miRNA, GOC:rph, PMID:15738428, PMID:21554756]
    +is_a: GO:0005487 ! nucleocytoplasmic transporter activity
    +created_by: dph
    +creation_date: 2015-06-29T08:59:16Z

     

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