Oddly it was working as of 3/23/2018 for me. As of this morning 3/24 it doesn't. Pressing F1 doesn't seem to take, F3, F4, F5 to change tabs and get color and x/y do register. I didn't see a D3 update notice so not sure what is going on. The only thing I can guess is that it no longer sees Diablo III.exe as focused.
When using the second skill setup pressing F5 gathers invalid coordinates and color...
When using a channeling skill (Whirlwind, Tempest rush) on left or right mouse button...