Compare the Top Safety Data Sheet (SDS) Software for Windows as of January 2026

What is Safety Data Sheet (SDS) Software for Windows?

Safety Data Sheet (SDS) software is designed to manage, store, and track Safety Data Sheets, which contain critical information about hazardous chemicals and materials. It simplifies compliance with safety regulations by organizing SDS documents in a centralized, digital repository accessible to all employees. With features like automated updates, version control, and quick search functionality, SDS software ensures that workers have immediate access to the latest safety information. Many solutions also offer reporting and tracking capabilities to monitor chemical inventory and flag potential risks. Ultimately, SDS software enhances workplace safety, ensures regulatory compliance, and minimizes the administrative burden of manual SDS management. Compare and read user reviews of the best Safety Data Sheet (SDS) software for Windows currently available using the table below. This list is updated regularly.

  • 1
    SafetyCulture

    SafetyCulture

    SafetyCulture

    SafetyCulture is a workplace operations platform trusted by 85,000+ teams to work safely, meet higher standards, and improve every day. 1. Streamline operations by eliminating paper processes - with simple checklists your teams can complete on any device. 2. Get the job done with seamless task and issue management - whether a team member spots something that needs fixing during an inspection, or while on the go, it’s easy to create and assign tasks to hold the right people accountable. 3. Reduce downtime with total asset visibility - gain unique visibility via sensors and telematics data o 4. Onboard, train, and upskill teams seamlessly - deliver bite-sized training that fits into the flow of your team’s work. No matter the device or location. 5. Workplace communications fit for the frontline - close the communication gap with a message system frontline teams love to use.
    Starting Price: $19.00/month/user
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  • 2
    Chemical Safety Software

    Chemical Safety Software

    SFS Chemical Safety

    Chemical Safety offers a comprehensive suite of environmental health and safety software applications. Features include GHS Labeling, Safety Data Sheets, Chemical Inventory Tracking, Hazardous Waste Management, Environmental Regulatory Reporting, and Employee Workplace Safety & Compliance. Everything you need to track your chemical inventory and hazardous waste from beginning to end. EMS addresses all of the special issues associated with storing, using, and disposing of hazardous materials. Safety Data Sheets: Manage and Distribute SDS's Online. A cloud-based safety data sheet management solution. Easy online access for all employees. Monitor and manage all aspects of employee and workplace safety including safe storage and use of chemicals, alerts and notifications, employee training requirements and site incident tracking with corrective actions.
  • 3
    SDScribe

    SDScribe

    SDScribe

    Create your own OSHA-compliant Safety Data Sheets (SDSs) in GHS format. Press a button and watch the SDS appear as an editable word-processing document. For the price that a consultant might charge to produce one or two SDSs, you can have your own SDS generator for all of your products. Included with the program is a generator for OSHA-mandated GHS labels. Also available as an option is the inventory and production manager, for preparing batches, maintaining raw material and product inventories, and more. One-time purchase with optional annual upgrades. Prepare an unlimited number of SDSs, with no per-page or per-SDS charges. Organized just like an SDS, with tabs that represent the individual sections and sub-sections of the SDS. Streamlined interface with color field titles to indicate the most important items to enter. Offers unlimited levels of mixture components when you add an ingredient that is itself a mixture.
    Starting Price: $1,395 one-time payment
  • 4
    VelocityEHS

    VelocityEHS

    VelocityEHS

    We deliver EHS management software that solves complex business challenges in simple ways. Our implementations are quicker, cost less and are more successful than traditional enterprise software systems. The real value of our solution is not the software itself, but how well it helps you do your job and achieve your goals — across departments, facilities, locations, and continents. Our true cloud solutions are simple enough for your frontline people to use on the fly, and sophisticated enough for you to run global, best-in-class programs — right out of the box. VelocityEHS brings together the industry’s most trusted solutions for managing risk, industrial hygiene, environmental concerns, hazards and incidents, training and much more. And we are the only source for MSDSonline chemical management and Humantech industrial and office ergonomics solutions. See why more than 18,000 customers worldwide trust us to simplify their complex compliance challenges.
  • 5
    GHSAuth

    GHSAuth

    Mar-Kov Computer Systems

    GHSAuth by Mar-Kov Computer Systems is a robust Global Harmonized Standard (GHS) compliant Safety Data Sheet (SDS) and Safety Label authoring tool for chemical manufacturers. GHSAuth lets EH&S staff manage and organize SDS documents for their organization, access a catalog of hazard codes and precautionary phrases, achieve SDS revision control and track changes, and so much more. The software package is available in both free and paid versions.
    Starting Price: $9.00/month/user
  • 6
    Vector EHS

    Vector EHS

    Vector Solutions

    The most cost-effective leader in EHS Management for over 15 years. Track essential EHS data via the web or on your mobile device with our comprehensive safety software suite. No matter the size, industry, or safety program, Vector EHS can be configured to meet your organization's needs. With an easy-to-use interface and highly praised customer support, managing your safety data will never be easier. Our EHS software is easy to use and allows all organizations, from global leaders to local businesses, to track, manage and comply with safety, environmental, and health regulations. Capabilities include: Incident Reporting, Mobile Inspections, Safety Metrics & Reports, Behavior Based Safety, Hazard Reporting, Job Safety Analysis, Online Employee Training, SDS & Chemical Management, and more. Vector EHS Management Software is built to meet the needs of some of the world's most critical industries.
  • 7
    EHS Insight

    EHS Insight

    EHS Insight

    EHS Insight is an environmental, health and safety (EHS) management platform that empowers organizations to ensure company-wide compliance. Affordable and quick to setup, EHS Insight offers the best value in EHS software today by providing businesses with the tools they need to manage incidents, audits and inspections, compliance obligations, corrective actions and more. EHS Insight also comes with fantastic support to assist businesses during and after software implementation.
    Starting Price: $200.00/month
  • 8
    sdsBinders

    sdsBinders

    Chemscape Safety Technologies

    Say goodbye to paper chaos and complexity with this simple to use SDS software solution that allows you to actively manage your chemicals and access your current SDS library online. Manage Safety Data Sheets with sdsBinders. Leave paper safety data sheets behind with our easy-to-use online SDS management software that provides you with immediate access to current safety data sheets & chemical safety information. SDS information your workers need to protect their health and safety. A solid foundation for chemical handling and regulatory compliance. More time to focus on other priorities and leave the SDS Management to us. Access your SDSs 24/7 from your own web portal. Our online SDS management service keeps your safety data sheets up-to-date, saving you time and giving you peace of mind that your SDS inventory is current and following all GHS regulatory requirements. Our SDS management software monitors your SDS library inventory and notifies you of any changes or issues.
  • 9
    CHEMDOX

    CHEMDOX

    CHEMDOX

    CHEMDOX® software supports regulatory experts in all aspects of hazardous materials management: - Chemical Management - Safety Data Sheet (SDS / MSDS) Authoring - Safety Data Sheet (SDS) Translation - Hazard Labeling - GHS Compliance - Safety Data Sheet (SDS) Distribution CHEMDOX® supports high-quality classifications with strong regulatory content and includes classification calculators for all included regulations. With CHEMDOX®, many hazardous materials management processes are automated and performed with database support.
  • 10
    Knowella

    Knowella

    Knowella

    Knowella helps organizations digitize and automate frontline operations, supply chain, and workplace safety-related programs, processes, and workflows; replacing paper, spreadsheets, and siloed tools with smart, no-code automation.
    Starting Price: $10/user/month
  • 11
    ExactSDS

    ExactSDS

    SDS Manager

    SDS Manager’s ExactSDS Authoring software helps businesses create accurate, compliant Safety Data Sheets quickly and efficiently. Designed for manufacturers, distributors, and EHS professionals, the cloud-based platform supports global regulations including GHS, OSHA, EU CLP, WHMIS, and REACH. Using intelligent automation and built-in regulatory logic, SDS Manager reduces manual effort, minimizes errors, and ensures consistency across all 16 SDS sections. The solution offers multi-language SDS authoring and translation, version control, chemical data management, and seamless updates to keep documents audit-ready at all times. Whether authoring a single SDS or managing a large SDS library, SDS Manager streamlines chemical compliance while saving time and resources. Ideal for companies seeking reliable, scalable, and globally compliant SDS creation software.
    Starting Price: $19/month
  • 12
    ExESS

    ExESS

    Lisam Systems

    ExESS® provides users a comprehensive and globally compliant solution for the authoring and distribution of safety data sheets. Built on flexible and scalable Microsoft .NET technology, ExESS is user friendly and can be installed on single workstations, over worldwide corporate networks or accessed and used via the cloud. In addition, country specific classifications such as the Austrian, VbF, the German; BetrSichV, Störfallverordnung and WGK, VOCs for EU, US and Swiss VOCV as well as Danish MAL and the US; NFPA and HMIS ratings are also provided in ExESS. Further, Lisam provides occupational exposure limit values and caters for biological limit values, SEVESO etc. The ExESS classification view allows users to review the actual calculation and data (including source) used to come to a final classification result.
  • 13
    ZLC OSHA Safety Manager
    The OSHA Safety Manager is a complete, integrated system for automating your injury and accident logging, and your programs for preventing them. It is based on Employee Views HRIS, with the additional safety functions added to it. The additional functions include injury log, for printing the OSHA 101/200 forms, and also for any other injuries you want to track but not print. The 200 form can be printed with full detail, or with the personal areas blank - ready for signing and posting. Automated Logic flowchart (series of questions) to help determine which events are required to be logged. Hazardous Materials Inventory and tracking of vendor's MSDS's (Material Safety Data Sheets). Better accuracy and coordination, all information in one place ensures all is up-to-date and accurate. All details presented in separate views, so you are never lost in the system. Unlimited history for every log, in complete detail.
  • 14
    SpheraCloud
    Empower your business with actionable and measurable results and gain a comprehensive view of ESG performance and risk in real time. For generations, companies found it near-impossible to generate a holistic view of their risk profiles. Today, they have SpheraCloud®, an integrated ESG performance and risk management software platform. SpheraCloud is a key part of Sphera’s approach to addressing safety and sustainability issues before they even occur. It allows users to not only get the right information to the right people at the right time, but also empowers them to make better business decisions with its predictive and prescriptive capabilities. Many companies struggle to connect disparate data throughout their organizations and their value chains, and to communicate that risk efficiently and effectively. It’s hard to complete such an enormous task—without SpheraCloud. The innovative SaaS platform empowers your company to gain a comprehensive view of ESG performance and risk.
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