Audience
Professionals requiring an advanced data access and analytics solution for biomarker discovery and patient stratification
About Signals Translational
With visual analytics powered by TIBCO Spotfire®, PerkinElmer Signals Translational provides all the necessary tools to harmonize, manage, search, aggregate and analyze data consistently across large datasets for use in translational research in a highly scalable manner. Powered by the industry-leading visual analytics platform TIBCO Spotfire®, Signals Translational enables precision medicine studies with the most advanced biomarker discovery and patient stratification solution available today. The Linear Mixed Effect App (LME) in Signals Translational allows scientists to rank the effect of multiple variables on a phenotype of interest, with the option to correct the effect of random variables in the analysis. The genes with the strongest impact on cancer stage progression can be identified independently of the origin of the patients. With the advantage of properly handling missing values and outliers, LME models are an effective tool to identify potential biomarkers.