Signals Inventa

ActivityBase is the established industry software platform for screening data management, with feature-rich data analysis tools, built-in object/compound registration tools and the industry standard database. ActivityBase provides analysis support for a wide range of biochemical, cellular and biophysical assay formats (including Ion Channel, FLIPR, Kinetic, SPR, Mass Spectrometry assays). The system integrates into HCS imaging stores (Perkin Elmer Columbus, Thermo Fisher HCS Studio, Molecular Devices MDCStore) for easy import of data and images. ActivityBase also features built-in compound registration and plate management tools. With ActivityBase, you can easily track and manage the results from years of assays in one system. The system can be configured to meet your needs, without having to buy new analysis packs, and, through improvements in your data analysis processes, can even increase your lab analysis tenfold.

With visual analytics powered by TIBCO Spotfire®, PerkinElmer Signals Translational provides all the necessary tools to harmonize, manage, search, aggregate and analyze data consistently across large datasets for use in translational research in a highly scalable manner. Powered by the industry-leading visual analytics platform TIBCO Spotfire®, Signals Translational enables precision medicine studies with the most advanced biomarker discovery and patient stratification solution available today. The Linear Mixed Effect App (LME) in Signals Translational allows scientists to rank the effect of multiple variables on a phenotype of interest, with the option to correct the effect of random variables in the analysis. The genes with the strongest impact on cancer stage progression can be identified independently of the origin of the patients. With the advantage of properly handling missing values and outliers, LME models are an effective tool to identify potential biomarkers.