Pixquare

Pixaki is the best pixel art app for iPad. It packs a whole load of features into a clean, modern interface, and it works great with Apple Pencil. So now you can make game sprites on the couch, animated backgrounds on your commute, or music videos in the park. Pixaki is packed with great tools dedicated to making pixel art. Drawing on the iPad with Apple Pencil feels smooth and natural. This is the most enjoyable way you can make pixel art. Turn on pixel perfect painting mode to automatically get rid off all those nasty double pixels when doing line art. This is going to save you a ton of time. As well as round and square brushes, Pixaki comes with the matrix dither brush with 13 different dither patterns. It works with the eraser too. The line tool makes it easy to create straight lines, which can optionally be locked to angles perfect for isometric art.

Pixen is a professional pixel art editor designed for working with low-resolution raster art, such as those 8-bit sprites found in old-school video games. Pixen packs all the tools pixel artists need in an intuitive, native interface including support for high zoom levels, animation editing, color palettes, and a lot more. Leverage Pixen's wide array of tools when composing pixel art: Pencil, Eraser, Brightness, Text, Eyedropper, Zoom, Rectangular Selection, Magic Wand, Lasso, Move, Fill, Line, Rectangle, and Ellipse. Take advantage of the flexibility layers provide when working with complex pixel art. Change opacity, blending modes, and more to compose creative effects. Use filters to adjust colors, create effects, and post-process your artwork. With Pixen, you can add and organize commonly-used colors into palettes. Pixen can even import and export color palettes in the Adobe Color Table, Microsoft Palette, JASC Palette, and GIMP Palette formats.