AutoGen

​Agno is a lightweight framework for building agents with memory, knowledge, tools, and reasoning. Developers use Agno to build reasoning agents, multimodal agents, teams of agents, and agentic workflows. Agno also provides a beautiful UI to chat with agents and tools to monitor and evaluate their performance. It is model-agnostic, providing a unified interface to over 23 model providers, with no lock-in. Agents instantiate in approximately 2μs on average (10,000x faster than LangGraph) and use about 3.75KiB memory on average (50x less than LangGraph). Agno supports reasoning as a first-class citizen, allowing agents to "think" and "analyze" using reasoning models, ReasoningTools, or a custom CoT+Tool-use approach. Agents are natively multimodal and capable of processing text, image, audio, and video inputs and outputs. The framework offers an advanced multi-agent architecture with three modes, route, collaborate, and coordinate.

AG2 is the open source AgentOS for building production-ready AI agents and multi-agent systems in minutes, not months. Formerly AutoGen, it provides an open source Python framework for building, orchestrating, and scaling AI agents that can collaborate through shared context, use tools, execute workflows, and support both autonomous and human-in-the-loop patterns. AG2 is designed for developers who want to build systems, not prompts, with simple and intuitive syntax, built-in conversation patterns, and a flexible platform for multi-agent automation. Agents in AG2 can extend their capabilities with tools, allowing them to interact with external systems, fetch real-time data, execute code, search the web, process documents, and complete complex tasks beyond a model’s internal knowledge. It supports many LLM providers and local models, including OpenAI-compatible endpoints, Anthropic Claude, Gemini through Vertex AI, DeepSeek, and LM Studio.