Compare the Top Laboratory Information Systems (LIS) for Mac as of May 2026

What are Laboratory Information Systems (LIS) for Mac?

Laboratory Information Systems (LIS) are software solutions designed to manage, track, and organize data and workflows in medical and research laboratories. They streamline the handling of patient information, sample tracking, and test results, ensuring accuracy and efficiency throughout the testing process. LIS integrates with other healthcare systems, such as electronic health records (EHR), to facilitate seamless data exchange and improve clinical decision-making. The system also supports regulatory compliance by maintaining detailed records, ensuring data security, and managing quality control. Ultimately, LIS enhances lab productivity, reduces errors, and improves the overall management of laboratory operations. Compare and read user reviews of the best Laboratory Information Systems (LIS) for Mac currently available using the table below. This list is updated regularly.

  • 1
    Apex LIS

    Apex LIS

    Apex Healthware, LLC

    Affordable Cloud-based LIS. Perfect for startup labs! Subscriptions start at $250/month including 3 analyzer interfaces unlimited users. CLIA-compliance suite makes it easy to comply with regulatory requirements. Easy-to-use application can be installed in a day and web-training available. LIS is easily configured to meet your exact analyzer and workflow requirements. HIPAA-compliant Phone app supports patient registration, test order and results notification. We have more than 300 deployments with clients specializing in: Fertility, Genetic testing, molecular testing, Pathology, Toxicology and virtually all other specialties. We have interfaced over 250 different analyzers including interfaces to the leading analyzers in the fields of molecular biology and genetic testing.
    Starting Price: $1500 one-time payment
  • 2
    Avalon Laboratory System

    Avalon Laboratory System

    Computer Service & Support

    Sophisticated and HIPAA-compliant, the Avalon Laboratory System is specifically designed to manage the production and billing needs of clinical, esoteric, and toxicology laboratories. Developed by Computer Service & Support(CSS), this modular laboratory information system offers an array of features for reference laboratory automation. The solution also provides a rich set of modules for microbiology, pain management and toxicology, rescheduling, remote laboratory, SQL Access, electronic medical records, pharmacogenomics, and more. In addition, there is Avalon BI (Business Intelligence) for billing. With Avalon LIS and Avalon BI running on the same platform, there is a reduction in errors and duplicate entry of data. The billing portion also offers up-front eligibility and diagnosis validity checking. In Avalon BI, there are even more robust reports for revenue cycle management.
  • 3
    LIS 365

    LIS 365

    LIS 365

    LIS 365 is a laboratory information system (LIS) software system that records, manages, and stores data for clinical & medical laboratories. A best LIS has traditionally been most adept at sending laboratory test orders to lab instruments, tracking those orders, and then recording the results. LIS Software should be used for the automation of workflows for the same purpose for which it is used to automate record keeping. This may not save you effort but it will definitely save you precious time. LIS365 also empowers laboratories to increase their revenues and enhance customer retention. We help them in boosting efficiency, streamline workflows, ensure patient satisfaction and safety. Commonly found functions in a LIS (laboratory information system) are the following, for instance Sample Management, Workflow management, reporting, EHR and ERP
    Starting Price: $5000.00/one-time/user
  • 4
    LigoLab LIS & RCM
    As a comprehensive enterprise-grade solution, the LigoLab LIS & RCM Laboratory Operating Platform™ includes modules for AP, CP, MDx, RCM, and Direct-to-Consumer, all on one integrated platform that supports the entire lifecycle of all cases, enabling laboratories to differentiate themselves in the marketplace, scale their operations, and become more profitable. The RCM module is deeply integrated with the LIS and automates ICD and CPT coding. Billing processes start at order inception with verification, eligibility, and scrubbing components that increase clean claim submissions and revenue, and decrease claim denials and compliance risk. TestDirectly is a patient engagement portal that enables labs and collection facilities to scale collection, testing, and reporting workflows that produce fast and accurate results, minus the friction and the errors that come with paper forms and manual labor.
  • 5
    SpeedsPath AP LIS
    SpeedsPath is a cloud-native AP LIS built to streamline the entire pathology workflow—from specimen accessioning and barcode tracking to grossing, histology, reporting, and digital archiving. Unlike outdated LIS systems that require heavy IT infrastructure, SpeedsPath is hosted in the cloud, making it accessible, scalable, and cost-efficient. Our platform provides pathology labs with a centralized, secure, and user-friendly system that automates routine processes, reduces manual errors, and ensures compliance with regulatory requirements like HIPAA, CLIA, and CAP.
    Starting Price: $0
  • 6
    newLab

    newLab

    newLab

    newLab Cloud is an AI-ready lab management platform built on ServiceNow. It helps biotech, pharmaceutical, and research organizations streamline workflows, manage laboratory equipment, and automate compliance processes. Designed for modern R&D environments, it offers equipment tracking, document management, workflow automation, and audit trails in one secure, cloud-based platform. With integrations for ServiceNow, newLab Cloud connects lab and IT operations to improve collaboration, ensure data integrity, and accelerate innovation.
  • 7
    AP Easy

    AP Easy

    AP Easy Software Solutions

    AP Easy Advanced is our leading on-premise laboratory information system designed specifically for anatomic pathology workflow. AP Easy Advanced is intuitive, easy to learn yet powerful and highly scalable. AP Easy Advanced comes in built with a Provider Portal allowing a labs clients to submit online orders and receive reports via our Integrated Provider portal. As well as a patient portal allowing you to setup patients so they can can view their own results and communicate with you at the lab via secure messages. AP Easy Advanced can interface with your electronic medical record software, billing software & lab instruments to provide a seamless operation for reducing data entry errors. AP Easy Advanced can also provide customizable report templates based on your lab requirements. The system is ideal for both large and small labs and offers both transactional/per case pricing or fixed monthly pricing options to our customers.
  • 8
    eHAT

    eHAT

    OrcaSys

    Electronic- Healthcare Administrative tool is a web-based, platform-independent, scalable and fully loaded hospital Information system developed using open source technology. eHAT comprises of 40 different modules to streamline the workflow of administrative, operational, revenue and clinical departments of a hospital. E-Hat Enterprise is fully loaded Hospital Management Information system with a one-stop solution specific to Large multi, super specialty and enterprise hospitals. eHAT Laboratory Information System is a web-based tool designed to improve efficiency in lab operations by automating manual processes. The software provides extensive support to daily lab operations right from sample collection to reporting which includes the recording, managing, storing and tracking of data. We use barcodes to create and update audit logs and chain of custody to automatically track where the sample is, in every stage of the process.
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