Best IT Security Software for Microsoft 365
View:
Compare the Top IT Security Software that integrates with Microsoft 365 as of October 2025
Sort By:
This a list of IT Security software that integrates with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.
What is IT Security Software for Microsoft 365?
IT security software is designed to protect information technology (IT) systems, networks, and data from cyber threats, such as malware, hacking, and unauthorized access. These tools provide various features such as antivirus protection, firewalls, encryption, intrusion detection and prevention systems, and vulnerability management to ensure the integrity, confidentiality, and availability of sensitive information. IT security software helps organizations detect, prevent, and respond to security incidents, mitigate risks, and ensure compliance with industry regulations. It is critical for businesses and individuals to safeguard against cyberattacks, data breaches, and other security vulnerabilities. Compare and read user reviews of the best IT Security software for Microsoft 365 currently available using the table below. This list is updated regularly.
-
1
Adaptive Security
Adaptive Security
Adaptive Security is OpenAI’s investment for AI cyber threats. Founded in 2024, Adaptive raised $50M+ from investors like OpenAI and a16z, as well as executives at Google Cloud, Fidelity, Shopify, and more. Adaptive protects customers from deepfakes, vishing, smishing, and AI email phishing with its next-generation security awareness training and phishing simulations. Security teams prepare employees for advanced threats with highly customized training that is role-based, enriched with OSINT, and even features deepfakes of their own executives. Employees train on mobile or desktop and rate the content an incredible 4.9/5 on average. Customers measure the success of their training program with AI-powered phishing tests. Realistic deepfake, voice, SMS, and email tests track risk across every vector. Trusted by Figma, the Dallas Mavericks, BMC, and others, Adaptive boasts a world-class NPS of 94. Want to learn more? Take a self-guided tour at adaptivesecurity.com. -
2
Blumira
Blumira
Empower Your Current Team to Achieve Enterprise-Level IT Security An all-in-one IT Security solution with SIEM, endpoint visibility, 24/7 monitoring, and automated response to reduce complexity, increase visibility and speed up time to respond. We handle the security heavy lifting, so you get time back in your day. With out-of-the-box detections, pre-filtered alerts, and response playbooks, your team can achieve real IT security value with Blumira. Quick Deployment, Immediate Results: Integrates with your tech stack and fully deploy, with no warm-up period, in hours All-You-Can-Eat Data Ingest: Predictable pricing and with unlimited data logging for full-lifecycle detection Compliance Made Easy: 1 year data retention included, pre-built reports, and 24/7 automated monitoring 99.7% CSAT Support: Solution Architects for product support, the Incident Detection and Response Team creating new detections, and 24/7 SecOps supportStarting Price: Free Trial -
3
Auth0
Okta
Auth0 takes a modern approach to Identity, providing secure access to any application, for any user. Safeguarding billions of login transactions each month, Auth0 delivers convenience, privacy, and security so customers can focus on innovation. Auth0 is part of Okta, The World’s Identity Company™. Auth0 lets you quickly integrate authentication and authorization for web, mobile, and legacy applications, with new Fine Grained Authorization (FGA) that goes beyond role-based access control. Authenticate users across all applications with a customized, secure, and standards-based single login. Universal Login connects users to a central authorization server. Credentials aren’t transferred across sources, which boosts security and protects against phishing and credential stuffing attacks. OAuth 2.0 recommends that only external user agents (like the browser) be used by native applications for authentication flows. Auth0’s Universal Login achieves this while enabling SSO.Starting Price: Free plan -
4
Comet Backup
Comet Backup
Start running backups and restores in less than 15 minutes! Fast, secure backup software for businesses and IT providers. Comet is a flexible, all-in-one backup platform available in 13 languages. You choose your backup destination, server location, configuration and setup. Backup to your own storage/location, SFTP, FTP or cloud storage provider (Wasabi, Amazon AWS, Google Cloud Storage, Microsoft Azure, Backblaze B2, or other S3-compatible cloud providers). Comet’s modern ‘chunking’ technology powers client-side deduplication with no full re-uploads after the first backup. Backups are incremental forever—your oldest backup can restore just as fast as your most recent. No need for differentials or delta-merging. Data is compressed and encrypted during backup, transit and rest. Test drive Comet Backup with a 30-day FREE trial!Starting Price: $19 per month -
5
Guardz
Guardz
Guardz is the unified cybersecurity platform purpose-built for MSPs. We consolidate the essential security controls, including identities, endpoints, email, awareness, and more, into one AI-native framework designed for operational efficiency. Our identity-centric approach connects the dots across vectors, reducing the gaps that siloed tools leave behind so MSPs can see, understand, and act on user risk in real time. Backed by an elite research and threat hunting team, Guardz strengthens detection across environments, turning signals into actionable insights. With 24/7 AI + human-led MDR, Guardz utilizes agentic AI to triage at machine speed while expert analysts validate, mitigate, and guide response, giving MSPs scalable protection without adding headcount. Our mission is simple: give MSPs the scale, confidence, and clarity they need to stay ahead of attackers and deliver protection to every SMB they serve. -
6
HERE Enterprise Browser
Here Enterprise Inc.
Built through collaboration with global banks, HERE Enterprise Browser provides enterprise security, workforce productivity and seamless integration of enterprise AI. HERE’s Chromium-based, zero-trust security model includes integration with Microsoft Entra and other IDPs, app access controls, data loss prevention controls, executable protection and auditability for compliance. HERE supercharges productivity through app interoperability and Supertabs that combine multiple tabs into persona or task-based dashboards. It provides federated enterprise search to Microsoft 365, Google Workspace, Salesforce and other platforms. HERE also has its own Notification Center and an AI Center that enables integration of enterprise AI models into end user workflows. The company is backed by major banks and IQT, the not-for-profit strategic investor that accelerates the introduction of groundbreaking technologies to enhance the national security of America and its allies. -
7
Safetica
Safetica
Safetica Intelligent Data Security protects sensitive enterprise data wherever your team uses it. With advanced data discovery, context-aware classification, proactive threat prevention and adaptive security, Safetica provides comprehensive visibility and control over your data. ✔️ Discover what to protect: Precisely locate personally identifiable information, intellectual property, financials, and more wherever it is used across the enterprise, cloud, and endpoint devices. ✔️ Prevent threats: Understand and mitigate risky behavior with automatic detection of suspicious file access, email communication and web browsing. Get the alerts you need to proactively uncover risk and prevent data breaches. ✔️ Keep your data safe: Intercept unauthorized exposure of sensitive personal data, trade secrets and intellectual property. ✔️ Work smarter: Help teams work, with in-moment data handling cues as they access and share sensitive information. -
8
Files.com
Files.com
6,000+ companies trust Files.com to automate and secure business critical transfers. We obsess about security, compliance, reliability, and performance so your critical business processes just work every time. Easily manage any transfer flow without writing scripts or code, and onboard workloads and partners effortlessly. We support standard file transfer protocols (FTP, SFTP, AS2) for working with external partners and also provide native apps for high performance internal transfers. As a fully Cloud-Native SaaS, there are no servers for you to buy or maintain, there is no installation required, and high availability and redundancy are built in and free. Out-of-the-box integrations include Microsoft (Azure, SharePoint, OneDrive, Active Directory & Office), AWS (S3 & SNS), Google (Cloud & Drive), Box, Dropbox, Zapier, and dozens of others. Developers can leverage our SDKs, API, and CLI to build custom integrations too. -
9
SpamTitan
TitanHQ
SpamTitan email security is an email spam filter for businesses, smbs, MSPs, and schools. SpamTitan email security blocks spam as well as phishing and day-zero attacks, viruses, malware, ransomware, and other email threats. Helps control mail flow, clean it, and protect against unwanted email. We provide easy-to-use yet advanced email security for businesses, smbs and MSPs that are Office365 friendly. SpamTitan - Premium functionality included: • CEO Impersonation protection • Phishing/ Spear phishing protection • Link analysis • Full Sandboxing • Zero Day Attacks protection • Mail Spooling • Spoofing protection • Malware and Ransomware protection • SPF/DKIM/DMARC checking • Encryption • Fully multitenant environment • Ability to rebrand the entire UI • Full REST API: • Comprehensive support and set up docs Try a FREE, fully supported trial of SpamTitan Email Security today.Starting Price: $2.14/user/month -
10
Kandji
Kandji
We’re Kandji: the Apple device management and security platform that empowers secure and productive global work. Through advanced automation and thoughtful experiences, we’re bringing much-needed harmony to the way admins, end-users, and global teams work today and tomorrow. Kandji brings zero-touch deployment, self-healing remediation, click-and-go security, and powerful automation to boost technology teams' efficiency while improving the employee experience with their work. -
11
phoenixNAP
phoenixNAP
phoenixNAP is a global IaaS provider delivering world-class infrastructure solutions from strategic edge locations in the U.S., Europe, Asia-Pacific, Australia, and Latin America. Specializing in performance, security, and availability, the company provides vastly redundant systems, unsurpassed security, high-density deployments, and flexibility to service from ¼ cabinets to private cage environments. Its Bare Metal Cloud solution provides access to 3rd Gen Intel® Xeon® Scalable Processors for advanced infrastructure performance and reliability. phoenixNAP offers a 100% uptime guarantee, an extensive server lineup, global connectivity options, flexible SLAs, and 24x7x365 live support to help businesses achieve their business objectives. Deploy high-performance, scalable cloud solutions for your growing IT needs, along with the security and reliability that you require at opex-friendly pricing plans.Starting Price: $0.10/hour -
12
ManageEngine ADManager Plus
ManageEngine
ADManager Plus is a simple, easy-to-use Windows Active Directory (AD) management and reporting solution that helps AD administrators and help desk technicians in their day-to-day activities. With a centralized and intuitive web-based GUI, the software handles a variety of complex tasks like bulk management of user accounts and other AD objects, delegates role-based access to help desk technicians, and generates an exhaustive list of AD reports, some of which are an essential requirement to satisfy compliance audits. This Active Directory tool also offers mobile AD apps that empower AD admins and technicians to perform important user management tasks, on the move, right from their mobile devices. Create multiple users and groups in Office 365, manage licenses, create Exchange mailboxes, migrate mailboxes, set storage limits, add proxy addresses, and more.Starting Price: $595 per year -
13
ManageEngine ADSelfService Plus
ManageEngine
ADSelfService Plus is an on-premises access management solution that caters to businesses across various industries, such as IT, banking, engineering, education, aviation, and telecommunications. Key features include: 1. Self-service password resets and account unlocks: Users can reset their passwords in AD and unlock their domain accounts from a web browser. 2. MFA: Machine logins, VPN and OWA logins, and cloud app logins can be secured using MFA. 3. Password synchronizer and SSO: Users can log in to multiple apps using one unified identity via SSO and real-time password synchronization. 4. Password policy enforcer: Admins can configure custom password policies to enforce strong password creation. 5. Password expiration notifier: Admins can send end users password expiration notifications via SMS or email. 6. Directory self-update: Users can update their AD attribute information through the directory self-update feature.Starting Price: $595 for 500 domain users/year -
14
Syncro
Syncro
Syncro offers the first Extended Monitoring and Management (XMM) platform purpose-built for midsized MSPs and internal IT teams. The unified platform integrates RMM (endpoint management), professional services automation (PSA), and Microsoft 365 multi-tenant management to help organizations simplify operations, strengthen security, and scale profitably. Syncro delivers powerful automation, native AI capabilities, deep Microsoft 365 integration, and seamless support for 50+ third-party tools—enabling teams to reduce complexity, cut costs, and uncover new revenue opportunities. Its transparent per-user pricing model and commitment to continuous innovation make it an ideal solution for modern IT operations. Learn more at syncromsp.com or follow Syncro on LinkedIn.Starting Price: $129 per user per month -
15
Keeper Security
Keeper Security
Keeper Security is transforming the way people and organizations around the world secure their passwords and passkeys, secrets and confidential information. Keeper’s easy-to-use cybersecurity platform is built on a foundation of zero-trust and zero-knowledge security to protect every user on every device. Keeper’s solution deploys in minutes and seamlessly integrates with any tech stack to prevent breaches, reduce help desk costs and ensure compliance. Trusted by millions of individuals and thousands of organizations globally, Keeper is the leader for best-in-class password and passkey management, secrets management, privileged access, secure remote access and encrypted messaging. Protect what matters at KeeperSecurity.com.Starting Price: $2.00 per user, per month -
16
NeoCertified Secure Email
NeoCertified
NeoCertified protects sensitive information through our secure email application across our versatile Cloud-based platform on any web browser, through Microsoft Office 365/Outlook plug-ins, and Gmail integration. iPhone + Android mobile apps are also available directly on your mobile devices. We have provided federally compliant, secure email solutions since 2002, and have helped businesses send and receive secure emails on any web browser or mobile device. NeoCertified also works across all email providers to give businesses the flexibility and assured protection they desire and deserve.Starting Price: $99.00/year/user -
17
E3:Universal
Paraben Corporation
Don’t get caught up in tools that are unmanageable. The E3 Platform gets you processing all types of digital evidence quickly with an Easy interface, Efficient engines, and Effective workflow. E3:UNIVERSAL version that is designed to do all data types from hard drive data, smartphones, and IoT data. The need to change around your tool based on what type of digital data you have is a thing of the past. The E3 Forensic Platform seamlessly adds a large variety of evidence into a single interface to be able to search, parse, review and report on the digital data from most digital sources. Computer forensics focuses on bits and bytes of the file system that holds a large variety of different valuable pieces of data that can be the key to your investigation. From the FAT files systems of old to modern file systems like Xboxes, the E3 Forensic Platform works with the powerhouse of multi-tasking analysis engines to breakdown the data.Starting Price: $6,295 -
18
SharePass
SharePass
SharePass is a SaaS Secret Management platform that allows sharing and managing secrets and confidential information using a web application, extension, or mobile app. SharePass works with encrypted links transmitted from the sender to the receiver with various settings and flags. The settings include expiry restriction, availability, IP restrictions and an entire filtering funnel (patent pending). SharePass is platform-independent that can be used with your existing communication tools. When it comes to your privacy, SharePass or any of its employees cannot see the content of your secrets; the secrets can be seen only by the exchanging parties. SharePass meets the latest cybersecurity compliance and regulations. In the era of identity theft, SharePass will protect you and prevent your data from leaking to the dark web by eliminating your digital footprint. SharePass supports SSO with Office365, Google Workspace, MFA, and integration with Yubikeys for maximum security.Starting Price: Free -
19
Easy365Manager
Agema A/S
Remove all pain from Office 365 management. Manage everything from AD Users & Computers. Eliminate Exchange on-premises. Easy365Manager integrates Office 365 with AD management, eliminating the need to constantly log in to web consoles and run PowerShell. Easy365Manager extends the functionality of AD Users & Computers by adding two new tabs to user properties. This allows you to manage EXO mailboxes directly from AD user properties - even complex settings like calendar delegation that otherwise require complex PowerShell scripting. Easy365Manager will allow your first-level supporter to work lightning-fast and reduce the number of tickets that are escalated to senior admins. Easy365Manager installs to any PC or server that has AD Users & Computers. There is no server component, service, AD extension, or custom security layer. You can install and configure Easy365Manager in less than two minutes and instantly eliminate all pain from hybrid Office 365 Management.Starting Price: $84 per year -
20
GlassWire
GlassWire
Instantly see who or what your PC is talking to on GlassWire's network monitoring graph, plus see what your PC may have connected to in the past. Detect spyware, malware, badly behaving apps, and bandwidth hogs, then block their connections. Monitor other PCs on your network and get alerted when new unknown devices join your WiFi. GlassWire warns you of network related changes to your PC, or unusual changes to your apps that could indicate malware. GlassWire offer a Consumer Solution and a Business solution, to suit the needs of both personal users and IT professionals. Among the features: Real-Time Monitoring to keep an eye on active and past network activity Threat. Threat Detection. GlassWire's built-in firewall detects and blocks potential threats. Application Tracking to Identify which applications are using your network and track their usage patterns. Bandwidth Usage, to stay informed about data consumption, And many more!Starting Price: $35.88/year/user -
21
Hoxhunt
Hoxhunt
Hoxhunt is a Human Risk Management platform that goes beyond security awareness to drive behavior change and (measurably) lower risk. Hoxhunt combines AI and behavioral science to create individualized micro-training experiences users love, so employees learn to detect and report advanced phishing attacks. Automated incident remediation helps operations teams respond fast with limited resources. Security leaders gain outcome-driven metrics to document reduced cybersecurity risk. Hoxhunt works with leading global companies such as Airbus, IGT, DocuSign, Nokia, AES, Avanade, and Kärcher, and partners with leading global cybersecurity companies such as Microsoft and Deloitte. -
22
Microsoft Authenticator
Microsoft
Go passwordless. Enter your username and confirm your sign-in with your phone. It’s that easy! Passwords can be forgotten, stolen, or compromised. With Authenticator, your phone provides an extra layer of security on top of your PIN or fingerprint. Use Authenticator to sign-in to Outlook, OneDrive, Office, and more. Protect all of your accounts with two-step verification. The app also helps you secure all of your online accounts by using the industry standard time-based OTP (one-time password) codes. -
23
FileWall
Odix
odix - a market leader in Enterprise CDR (Content Disarm and Reconstruction), is now offering FileWall, a native cybersecurity application for Microsoft Office 365 mailboxes for SMEs. FileWall™ is designed to run in conjunction with existing Microsoft security solutions such as EOP and ATP, ensuring complete prevention against unknown attacks delivered via email attachments. FileWall™ doesn’t harm/change any of Microsoft sender related security capabilities.Starting Price: $1 per user, per month -
24
Vinchin Backup & Recovery
Vinchin
Vinchin Backup & Recovery, a comprehensive next-generation backup solution self-developed by Vinchin, supports the world’s most mainstream virtual environments including VMware, Hyper-V, XenServer, XCP-ng, oVirt, RHV, Oracle OLVM, Sangfor HCl, OpenStack, Huawei FusionCompute(Xen Based), H3C CAS/UIS, ZStack, Proxmox, database including Oracle DB, MySQL, SQL Server, PostgreSQL, Postgres Pro, MariaDB, Windows and Linux physical machines, file shares/NAS, and supports cross-platforms recovery or migration, backup verification, cloud archive, offsite copy, ransomware protection and other data protection features. It prevents the loss of critical business data due to human misoperation, viruses, attacks, hardware failures, natural disasters, wars, etc. -
25
N-able Mail Assure
N-able
N-able Mail Assure cloud-based email security solution provides advanced threat protection for inbound and outbound email using collective threat intelligence, 24/7 email continuity, and long-term email archiving. The service includes a multitenant web-interface with predefined settings, reporting, and views designed to ensure control and visibility over email flows. N-able Mail Assure’s proprietary technology incorporates input from processing large volumes of email data that feeds the Intelligent Protection and Filtering Engine. This combined with real-time pattern threat recognition leveraging a variety of filtering technologies help protect against spam, viruses, phishing attacks, impersonation, spoofing, malware, and other email-borne threats. -
26
Aid4Mail
Fookes Software Ltd
Aid4Mail is a fast, reliable, and highly accurate tool to collect, recover, search, and convert emails. It supports most mailbox file formats (e.g. PST, OST, OLM, mbox), IMAP accounts (e.g. Yahoo! Mail, AOL) and popular mail service providers (e.g. Microsoft 365, Exchange, Gmail). Aid4Mail can recover double-deleted messages and corrupted emails, and extract MIME data from certain types of unknown file formats through file carving. Aid4Mail provides a large array of tools to search and filter out unwanted emails during conversion. Save time by using native pre-acquisition filters to download a subset of your mail from Exchange, Office 365, Gmail and other webmail services. Use Aid4Mail’s integrated search engine to cull-down your email collection. Its search operators are very similar to Gmail and Office 365. Aid4Mail is used by Fortune 500 companies, government agencies and legal professionals around the world. It is made in Switzerland by perfectionists.Starting Price: $59.95 -
27
WebTitan
TitanHQ
WebTitan is a DNS Based Web content filter and Web security layer that blocks cyber attacks, malware, ransomware and malicious phishing as well as providing granular web content control. WebTitan DNS filtering filters over 2 billion DNS requests every day and identifies 300,000 malware iterations a day. Our intelligent AI driven real time content categorization engine combines industry leading anti-virus and cloud based architecture. This makes the WebTitan Cloud DNS filter an ideal solution for organizations needing maximum protection and minimal maintenance. This cloud based web filtering solution provides complete protection from online threats such as viruses, malware, ransomware, phishing and comprehensive content filtering. WebTitan Cloud is a low maintenance solution that can be set up in five minutes to stop your users from accessing inappropriate content online. Start your free Trial of WebTitan today, with full support included. -
28
Unitrends Backup
Kaseya
Unitrends Unified Backup platform protects your data no matter where it lives. A complete and agile platform, Unitrends offers protection for on-premises infrastructure, cloud-based workloads, SaaS applications and remote endpoints devices like PCs and workstations. Integrations with remote management, security and IT documentation tools provide end-to-end protection from human error, cyberthreats and inject automation and artificial intelligence to simplify complex systems. Managed through a singular portal, Unitrends offers a unified experience with visibility and control across a complete backup infrastructure. -
29
N‑able Passportal
N-able
N‑able™ Passportal™ provides simple yet secure password and documentation management tailored for the operations of an MSP and ITSP. The platform is cloud-based and offers channel partners automated password protection and makes storing, managing, and retrieving passwords and client knowledge quick and easy from virtually any connected device. The N‑able™ Passportal™ product suite also offers value-added service products including Documentation Manager™, Blink™ and Site™ all of which promote compliance with industry regulations and help protect businesses from data breaches, cybersecurity threats, and network vulnerabilities.Starting Price: $18.00/month -
30
SpinOne
Spin.AI
SpinOne is an all-in-one, SaaS security platform that protects SaaS data for mission-critical SaaS applications, including Google Workplace, Microsoft 365, Salesforce and Slack, by delivering full visibility and fast incident response. It eliminates fundamental security and management challenges associated with protecting SaaS data by reducing the risk of data leak and data loss, saving time for SecOps teams through automation, reducing downtime and recovery costs from ransomware attacks, and improving compliance. SpinOne solutions include: -SaaS Backup & Recovery -SaaS Ransomware Detection & Response -SaaS Data Leak Prevention & Data Loss Protection -SaaS Security Posture Management SpinOne also integrates with popular business apps – Jira, ServiceNow, DataDog, Splunk, Slack, and Teams – to help you save time and reduce manual workloads. Exciting News: Spin.AI recognized as a Strong Performer in The Forrester Wave™: SaaS Security Posture Management, Q4 2023 Report.