Compare the Top On-Premises HPC Software as of October 2025

What is On-Premises HPC Software?

High-Performance Computing (HPC) software are applications designed to maximize computational power, enabling complex and resource-intensive tasks to be executed efficiently. These programs optimize parallel processing, often leveraging supercomputers or distributed computing clusters to solve problems in fields like scientific research, engineering, and data analytics. HPC software includes components for workload management, data communication, and performance tuning, ensuring scalability and efficient resource utilization. Examples include simulation software, machine learning frameworks, and tools for weather modeling or molecular dynamics. By harnessing advanced algorithms and hardware, HPC software accelerates computation, reducing the time required for tasks that would otherwise take weeks or months on conventional systems. Compare and read user reviews of the best On-Premises HPC software currently available using the table below. This list is updated regularly.

  • 1
    Azure FXT Edge Filer
    Create cloud-integrated hybrid storage that works with your existing network-attached storage (NAS) and Azure Blob Storage. This on-premises caching appliance optimizes access to data in your datacenter, in Azure, or across a wide-area network (WAN). A combination of software and hardware, Microsoft Azure FXT Edge Filer delivers high throughput and low latency for hybrid storage infrastructure supporting high-performance computing (HPC) workloads.Scale-out clustering provides non-disruptive NAS performance scaling. Join up to 24 FXT nodes per cluster to scale to millions of IOPS and hundreds of GB/s. When you need performance and scale in file-based workloads, Azure FXT Edge Filer keeps your data on the fastest path to processing resources. Managing data storage is easy with Azure FXT Edge Filer. Shift aging data to Azure Blob Storage to keep it easily accessible with minimal latency. Balance on-premises and cloud storage.
  • 2
    Fuzzball
    Fuzzball accelerates innovation for researchers and scientists by eliminating the burdens of infrastructure provisioning and management. Fuzzball streamlines and optimizes high-performance computing (HPC) workload design and execution. A user-friendly GUI for designing, editing, and executing HPC jobs. Comprehensive control and automation of all HPC tasks via CLI. Automated data ingress and egress with full compliance logs. Native integration with GPUs and both on-prem and cloud storage on-prem and cloud storage. Human-readable, portable workflow files that execute anywhere. CIQ’s Fuzzball modernizes traditional HPC with an API-first, container-optimized architecture. Operating on Kubernetes, it provides all the security, performance, stability, and convenience found in modern software and infrastructure. Fuzzball not only abstracts the infrastructure layer but also automates the orchestration of complex workflows, driving greater efficiency and collaboration.
  • 3
    AWS Elastic Fabric Adapter (EFA)
    Elastic Fabric Adapter (EFA) is a network interface for Amazon EC2 instances that enables customers to run applications requiring high levels of inter-node communications at scale on AWS. Its custom-built operating system (OS) bypass hardware interface enhances the performance of inter-instance communications, which is critical to scaling these applications. With EFA, High-Performance Computing (HPC) applications using the Message Passing Interface (MPI) and Machine Learning (ML) applications using NVIDIA Collective Communications Library (NCCL) can scale to thousands of CPUs or GPUs. As a result, you get the application performance of on-premises HPC clusters with the on-demand elasticity and flexibility of the AWS cloud. EFA is available as an optional EC2 networking feature that you can enable on any supported EC2 instance at no additional cost. Plus, it works with the most commonly used interfaces, APIs, and libraries for inter-node communications.
  • 4
    Bright Cluster Manager
    NVIDIA Bright Cluster Manager offers fast deployment and end-to-end management for heterogeneous high-performance computing (HPC) and AI server clusters at the edge, in the data center, and in multi/hybrid-cloud environments. It automates provisioning and administration for clusters ranging in size from a couple of nodes to hundreds of thousands, supports CPU-based and NVIDIA GPU-accelerated systems, and enables orchestration with Kubernetes. Heterogeneous high-performance Linux clusters can be quickly built and managed with NVIDIA Bright Cluster Manager, supporting HPC, machine learning, and analytics applications that span from core to edge to cloud. NVIDIA Bright Cluster Manager is ideal for heterogeneous environments, supporting Arm® and x86-based CPU nodes, and is fully optimized for accelerated computing with NVIDIA GPUs and NVIDIA DGX™ systems.
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