ManageEngine Application Control Plus vs. VIPRE Endpoint Security Comparison Chart

ThreatLocker is a Zero Trust Platform that prevents cyber threats by blocking unknown applications, enforcing least privilege, and controlling what can run across your environment. Using Allowlisting, Ringfencing, Network Control, and more, ThreatLocker stops ransomware, zero-day attacks, and unauthorized activity before execution, rather than relying on detection after the fact. Built for modern IT and cybersecurity teams, the platform delivers centralized visibility and policy management across endpoints, users, and applications. ThreatLocker reduces attack surface, limits lateral movement, and supports compliance with detailed audit logs. With fast deployment, a large built-in application library, and streamlined approvals, organizations can strengthen security while minimizing operational overhead and maintaining business continuity.

Securden Endpoint Privilege Manager (EPM) helps enterprises remove admin rights without impacting productivity on Windows, Mac, and Linux endpoints. Securden EPM helps elevate applications for standard users and grant admin rights on a Just-in-Time basis, eliminating standing privileges while maintaining seamless operations. Enforce application control using allowlisting and blocklisting, enable on-demand and policy-based granular application elevation, and manage privileges even on offline endpoints. Capabilities include JIT local admin rights, application usage tracking, and local administrator group monitoring. Secure remote access supports IT helpdesk operations, while built-in controls help meet compliance requirements such as HIPAA, PCI-DSS, GDPR, and NERC-CIP. A highly scalable architecture and wide array of integrations make Securden EPM ideal for securing enterprise endpoints at scale.

Securden Unified PAM is a privileged access security solution that lets you discover, centrally store, organize, share, manage, and keep track of all privileged identities, passwords, keys, documents, and other identities. It helps you establish a centralized password management system, automate management with approval workflows, control ‘who’ can access ‘what’, monitor, and record all access to critical IT assets, and enforce password security best practices. The major modules of Securden Unified PAM are password management, privileged account management, secure remote access, application control, endpoint privilege management, privileged session management, and SSH key management. The platform supports compliance with NIS2, DORA, NIST, PCI-DSS, HIPAA, and ISO-IEC 27001. Installation typically takes only a few minutes, and a complete production-ready PAM can be achieved in less than a month with Securden Unified PAM.

ManageEngine Endpoint Central gives IT teams a single platform to manage and secure every device across the organization, eliminating the need to juggle multiple point tools. Patch management is automated across Windows, macOS, Linux, and 1000+ third-party applications. Software deployment, OS imaging, and remote desktop capabilities allow administrators to provision, update, and troubleshoot endpoints without physical presence. Security capabilities include vulnerability assessment, application control, device control, browser security, endpoint privilege management, EDR, NGAV protection against malware and zero-day threats, and private access for secure remote connectivity. BitLocker and FileVault encryption management adds data protection across Windows and macOS fleets. Mobile device management extends control to iOS and Android, supporting corporate-owned and BYOD environments. Available on-premises or in the cloud across five editions: Free, Professional, Enterprise, UEM, and Security.

Admin By Request EPM gives organizations control over who and what can elevate on their endpoints, without standing up servers, databases, or a dedicated admin team to run it. The model is least privilege: a user or an application receives the specific access its task requires and nothing more. This closes off a common attack route, since permanent local admin rights are what an attacker inherits when malware executes or a credential is stolen. Removing admin rights does not push users back into support queues. When someone needs a longer stretch of elevated work, they run an Admin Session that expires on its own. When they need only one program elevated, Run As Admin handles that alone and leaves the rest of the system unprivileged. Requests can be approved through the portal, the mobile app, or the API. Files receive an OPSWAT MetaDefender reputation check before elevation, and software that has already been vetted can clear automatically through pre-approval or the AI and Machine Learning approval engine. A single agent supports Windows, macOS, and Linux and behaves the same whether the endpoint is online or offline. Auditing and inventory are included as standard.

Airlock Digital is an application control solution that enforces a Deny by Default security posture. It enables organizations to define trusted applications, scripts, libraries, and processes at a granular level using file hash, path, publisher, or parent process. Only those explicitly defined as trusted are allowed to execute. The platform supports Windows, macOS, and Linux systems, including legacy operating systems and operational technology (OT) environments. Airlock Digital includes allowlisting and blocklisting capabilities, integrated file reputation checks via VirusTotal, and detailed logging for audit and compliance. Exception management is supported through features such as rule-based overrides and time-bound One-Time Passwords (OTPs). Centralized policy management allows consistent enforcement across large and distributed environments. The platform is available as an on-premises deployment, in the cloud, or as a managed hosted service.

Iru (formerly Kandji) is an all-in-one, AI-powered security and compliance platform designed to simplify IT management and strengthen enterprise protection. Built on the Iru Context Model, it unifies identity, endpoint, and compliance into a single intelligent system that understands users, devices, and applications in context. With passwordless workforce identity, advanced endpoint detection, and automated compliance, Iru delivers both security and efficiency without the complexity of multiple tools. Its integrated approach enables IT teams to secure access, prevent threats, and maintain continuous audit readiness—all from one intuitive platform. Trusted by over 5,000 companies including Plaid, Notion, Airbus, and Vercel, Iru transforms how modern businesses manage digital trust. The result is reduced IT workload, improved employee experience, and enterprise-grade protection built for the AI era.

ESET Protect Advanced is a comprehensive cybersecurity solution designed for businesses of all sizes. It offers advanced endpoint protection against ransomware, zero-day threats, and sophisticated attacks with ESET LiveSense technology. It includes full disk encryption for legal compliance and data protection. The solution features proactive cloud-based threat defense using adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis to prevent new threats. Mobile threat defense secures Android and iOS devices with anti-malware, anti-theft, and mobile device management. It also provides cloud app protection, mail server security, and vulnerability and patch management. Extended detection and response (XDR) enhances threat detection and response, while multi-factor authentication adds security. The solution offers single-pane-of-glass remote management for visibility into threats and users, along with advanced reporting and custom notifications.

NinjaOne unifies IT to simplify work for 35,000+ customers in 140+ countries. The NinjaOne Unified IT Operations Platform delivers endpoint management, autonomous patching, backup, and remote access in a single console to improve efficiency, increase resilience, and reduce spend. By automating IT and managing all endpoints, organizations give employees a great technology experience to work faster, smarter, and easier while IT teams modernize and improve efficiency. NinjaOne is a Leader in the Gartner Magic Quadrant for Endpoint Management Tools. The company is obsessed with customer success and has retained a 98% customer satisfaction score for more than 5 years.

Safetica delivers Intelligent Data Security. Its AI-powered platform helps security teams see and control how sensitive data is used across endpoints, cloud applications, and AI, so they can prevent data loss, reduce insider risk, and support compliance without disrupting productive work. Safetica AI Protection gives teams visibility into AI activity and sensitive data sharing, with controls that protect data while enabling productive AI use. ✔️ Data Protection: Classify, monitor, and control sensitive data across endpoints, cloud applications, and AI interactions in real time. ✔️ Insider Risk and User Behavior: Identify risky and anomalous activity to reduce the risk of careless data handling, compromised accounts, and malicious actions. ✔️ Compliance and Data Discovery: Discover and classify sensitive data, then use audit-ready reporting to support compliance across data at rest, in motion, and in use. ✔️ Cloud Security: Protect sensitive data across Microsoft 365 and other cloud and file-sharing platforms by monitoring and classifying files and enforcing policies on file activity.