LigPlot+

LigPlot+

EMBL-EBI
SILCS

SILCS

SilcsBio
LigPlot+ SILCS

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LigPlot+:

About

LigPlot+ is a successor to our original LIGPLOT program for the automatic generation of 2D ligand-protein interaction diagrams. It is run from an intuitive java interface that allows on-screen editing of the plots via mouse click-and-drag operations. In addition to the new interface, the program includes several major enhancements over the old version. When two or more ligand-protein complexes are sufficiently similar, LigPlot+ can automatically display their interaction diagrams either superposed or side by side. Any conserved interactions are highlighted. The LigPlot+ suite also now includes an update of the original DIMPLOT program for plotting protein-protein or domain-domain interactions. Users can flexibly select the interface of interest and DIMPLOT will then generate a diagram showing the residue-residue interactions across the interface. To assist in interpretation, the residues in one of the interfaces can be optionally displayed in sequence order.
SILCS:

About

Site-Identification by Ligand Competitive Saturation (SILCS) generates 3D maps (FragMaps) of interaction patterns for chemical functional groups with your target molecule. Site-Identification by Ligand Competitive Saturation (SILCS) generates 3D maps (FragMaps) of interaction patterns for chemical functional groups with your target molecule. SILCS reveals intricacies of dynamics and provides tools to optimize ligand scaffolds using qualitative and quantitative binding pockets insights allowing more rapid and effective drug design. SILCS uses multiple small molecule probes with various functional groups, explicit solvent modeling, and target molecule flexibility to perform protein target mapping. Visualize favorable interactions with the target macromolecule. Gain insights to design better ligands with optimally placed functional groups.
LigPlot+:

Platforms Supported

Windows Supported
Mac Supported
Linux Supported
Cloud Not Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
SILCS:

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
LigPlot+:

Audience

Labs and researchers interested in a solution to create and visualize ligand-protein interaction diagrams
SILCS:

Audience

Laboratories searching for a dynamic molecule design software to create end-to-end drug design workflows
LigPlot+:

Support

Phone Support Supported
24/7 Live Support Not Supported
Online Supported
SILCS:

Support

Phone Support Supported
24/7 Live Support Not Supported
Online Supported
LigPlot+:

API

Offers API Not Supported
SILCS:

API

Offers API Not Supported
LigPlot+:

Screenshots and Videos

SILCS:

Screenshots and Videos

LigPlot+:

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported
SILCS:

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported
LigPlot+:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
SILCS:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
LigPlot+:

Training

Documentation Supported
Webinars Supported
Live Online Not Supported
In Person Supported
SILCS:

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported
LigPlot+:

Company Information

EMBL-EBI
United Kingdom
www.ebi.ac.uk/thornton-srv/software/LigPlus/
SILCS:

Company Information

SilcsBio
Founded: 2012
United States
silcsbio.com/software/
LigPlot+:

Alternatives

SILCS

SILCS

SilcsBio
SILCS:

Alternatives

Aurora Drug Discovery

Aurora Drug Discovery

Aurora Fine Chemicals
LigPlot+:
3decision

3decision

Discngine
SILCS:
3decision

3decision

Discngine
LigPlot+:
Aurora Drug Discovery

Aurora Drug Discovery

Aurora Fine Chemicals
SILCS:
LigPlot+:
SILCS:
LigPlot+

LigPlot+

EMBL-EBI
LigPlot+:
SILCS:
LigPlot+:

Categories

Drug Discovery Supported
SILCS:

Categories

Drug Discovery Supported
LigPlot+:

Integrations

No info available.
SILCS:

Integrations

No info available.
LigPlot+:
Claim LigPlot+ and update features and information
Claim LigPlot+ and update features and information
SILCS:
Claim SILCS and update features and information
Claim SILCS and update features and information