NVIDIA BioNeMoNVIDIA
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Evo 2Arc Institute
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About
BioNeMo is an AI-powered drug discovery cloud service and framework built on NVIDIA NeMo Megatron for training and deploying large biomolecular transformer AI models at a supercomputing scale. The service includes pre-trained large language models (LLMs) and native support for common file formats for proteins, DNA, RNA, and chemistry, providing data loaders for SMILES for molecular structures and FASTA for amino acid and nucleotide sequences. The BioNeMo framework will also be available for download for running on your own infrastructure. ESM-1, based on Meta AI’s state-of-the-art ESM-1b, and ProtT5 are transformer-based protein language models that can be used to generate learned embeddings for tasks like protein structure and property prediction. OpenFold, a deep learning model for 3D structure prediction of novel protein sequences, will be available in BioNeMo service.
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About
Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.
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Platforms Supported
Windows
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Mac
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Linux
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Cloud
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On-Premises
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iPhone
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iPad
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Android
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Chromebook
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Platforms Supported
Windows
Not Supported
Mac
Not Supported
Linux
Not Supported
Cloud
Supported
On-Premises
Not Supported
iPhone
Not Supported
iPad
Not Supported
Android
Not Supported
Chromebook
Not Supported
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Audience
Organizations looking for a powerful Drug Discovery solution
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Audience
Computational biologists and genetic engineers in need of a tool to model and design biological sequences across multiple modalities, enhancing research in genomics and synthetic biology
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Support
Phone Support
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24/7 Live Support
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Online
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Support
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24/7 Live Support
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Online
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API
Offers API
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API
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Pricing
No information available.
Free Version
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Free Trial
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Pricing
No information available.
Free Version
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Reviews/
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Training
Documentation
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Webinars
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Live Online
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In Person
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Training
Documentation
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Company InformationNVIDIA
Founded: 1993
United States
www.nvidia.com/en-us/gpu-cloud/bionemo/
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Company InformationArc Institute
United States
arcinstitute.org/tools/evo
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Integrations
Evo 2
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Evo Designer
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GitHub
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Hugging Face
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NVIDIA AI Foundations
Supported
NVIDIA BioNeMo
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NVIDIA Clara
Supported
NVIDIA NeMo Megatron
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Integrations
Evo 2
Not Supported
Evo Designer
Supported
GitHub
Supported
Hugging Face
Supported
NVIDIA AI Foundations
Not Supported
NVIDIA BioNeMo
Supported
NVIDIA Clara
Not Supported
NVIDIA NeMo Megatron
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