ESMC

ESMC

Biohub
NVIDIA BioNeMo ESMC

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NVIDIA BioNeMo:

About

BioNeMo is an AI-powered drug discovery cloud service and framework built on NVIDIA NeMo Megatron for training and deploying large biomolecular transformer AI models at a supercomputing scale. The service includes pre-trained large language models (LLMs) and native support for common file formats for proteins, DNA, RNA, and chemistry, providing data loaders for SMILES for molecular structures and FASTA for amino acid and nucleotide sequences. The BioNeMo framework will also be available for download for running on your own infrastructure. ESM-1, based on Meta AI’s state-of-the-art ESM-1b, and ProtT5 are transformer-based protein language models that can be used to generate learned embeddings for tasks like protein structure and property prediction. OpenFold, a deep learning model for 3D structure prediction of novel protein sequences, will be available in BioNeMo service.
ESMC:

About

ESMC is the latest in the ESM family of protein language models, establishing a new frontier in representation learning for protein biology. Trained on billions of evolutionary sequences, it learns representations that reflect a mechanistic reduction of protein structure and function. The model is built on a transformer architecture, supports sequences as its core modality, and is trained on up to 6 billion proteins. ESMC is designed for protein science research, including structure prediction, function annotation, protein design, and understanding evolutionary relationships between proteins. It can generate novel proteins from partial sequence, structure, or functional constraints, helping researchers explore new possibilities in protein design and biological discovery. The Biohub Platform provides access to ESMC through the API and the ESM Python package, with quickstart resources for installing the package, creating an API key, connecting to the platform.
NVIDIA BioNeMo:

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
ESMC:

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
NVIDIA BioNeMo:

Audience

Organizations looking for a powerful Drug Discovery solution
ESMC:

Audience

Protein science researchers who need transformer-based sequence representations for structure prediction, function annotation, mutation analysis, and protein design
NVIDIA BioNeMo:

Support

Phone Support Supported
24/7 Live Support Not Supported
Online Supported
ESMC:

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported
NVIDIA BioNeMo:

API

Offers API Not Supported
ESMC:

API

Offers API Supported
NVIDIA BioNeMo:

Screenshots and Videos

ESMC:

Screenshots and Videos

NVIDIA BioNeMo:

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported
ESMC:

Pricing

Free
Free Version Supported
Free Trial Not Supported
NVIDIA BioNeMo:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
ESMC:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
NVIDIA BioNeMo:

Training

Documentation Supported
Webinars Supported
Live Online Not Supported
In Person Not Supported
ESMC:

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported
NVIDIA BioNeMo:

Company Information

NVIDIA
Founded: 1993
United States
www.nvidia.com/en-us/gpu-cloud/bionemo/
ESMC:

Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmc
NVIDIA BioNeMo:

Alternatives

ESMC:

Alternatives

NVIDIA BioNeMo:
Evo 2

Evo 2

Arc Institute
ESMC:
Evo 2

Evo 2

Arc Institute
NVIDIA BioNeMo:
ESMFold2

ESMFold2

Biohub
ESMC:
ESMFold2

ESMFold2

Biohub
NVIDIA BioNeMo:
ESMC:
NVIDIA BioNeMo:
ESMC

ESMC

Biohub
ESMC:
HyperProtein

HyperProtein

Hypercube
NVIDIA BioNeMo:

Categories

AI Science Supported
Drug Discovery Supported
Healthcare AI Supported
ESMC:

Categories

AI Models Supported
AI Science Supported
NVIDIA BioNeMo:

Integrations

Biohub Not Supported
Evo 2 Supported
NVIDIA AI Foundations Supported
NVIDIA Clara Supported
NVIDIA NeMo Megatron Supported
Python Not Supported
ESMC:

Integrations

Biohub Supported
Evo 2 Not Supported
NVIDIA AI Foundations Not Supported
NVIDIA Clara Not Supported
NVIDIA NeMo Megatron Not Supported
Python Supported
NVIDIA BioNeMo:
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Claim NVIDIA BioNeMo and update features and information
ESMC:
Claim ESMC and update features and information
Claim ESMC and update features and information