12Port vs. SysTools USB Blocker Software Comparison Chart

Securden Unified PAM is a privileged access security solution that lets you discover, centrally store, organize, share, manage, and keep track of all privileged identities, passwords, keys, documents, and other identities. It helps you establish a centralized password management system, automate management with approval workflows, control ‘who’ can access ‘what’, monitor, and record all access to critical IT assets, and enforce password security best practices. The major modules of Securden Unified PAM are password management, privileged account management, secure remote access, application control, endpoint privilege management, privileged session management, and SSH key management. The platform supports compliance with NIS2, DORA, NIST, PCI-DSS, HIPAA, and ISO-IEC 27001. Installation typically takes only a few minutes, and a complete production-ready PAM can be achieved in less than a month with Securden Unified PAM.

Admin By Request EPM gives organizations control over who and what can elevate on their endpoints, without standing up servers, databases, or a dedicated admin team to run it. The model is least privilege: a user or an application receives the specific access its task requires and nothing more. This closes off a common attack route, since permanent local admin rights are what an attacker inherits when malware executes or a credential is stolen. Removing admin rights does not push users back into support queues. When someone needs a longer stretch of elevated work, they run an Admin Session that expires on its own. When they need only one program elevated, Run As Admin handles that alone and leaves the rest of the system unprivileged. Requests can be approved through the portal, the mobile app, or the API. Files receive an OPSWAT MetaDefender reputation check before elevation, and software that has already been vetted can clear automatically through pre-approval or the AI and Machine Learning approval engine. A single agent supports Windows, macOS, and Linux and behaves the same whether the endpoint is online or offline. Auditing and inventory are included as standard.

Securden Endpoint Privilege Manager (EPM) helps enterprises remove admin rights without impacting productivity on Windows, Mac, and Linux endpoints. Securden EPM helps elevate applications for standard users and grant admin rights on a Just-in-Time basis, eliminating standing privileges while maintaining seamless operations. Enforce application control using allowlisting and blocklisting, enable on-demand and policy-based granular application elevation, and manage privileges even on offline endpoints. Capabilities include JIT local admin rights, application usage tracking, and local administrator group monitoring. Secure remote access supports IT helpdesk operations, while built-in controls help meet compliance requirements such as HIPAA, PCI-DSS, GDPR, and NERC-CIP. A highly scalable architecture and wide array of integrations make Securden EPM ideal for securing enterprise endpoints at scale.

ThreatLocker is a Zero Trust Platform that prevents cyber threats by blocking unknown applications, enforcing least privilege, and controlling what can run across your environment. Using Allowlisting, Ringfencing, Network Control, and more, ThreatLocker stops ransomware, zero-day attacks, and unauthorized activity before execution, rather than relying on detection after the fact. Built for modern IT and cybersecurity teams, the platform delivers centralized visibility and policy management across endpoints, users, and applications. ThreatLocker reduces attack surface, limits lateral movement, and supports compliance with detailed audit logs. With fast deployment, a large built-in application library, and streamlined approvals, organizations can strengthen security while minimizing operational overhead and maintaining business continuity.

Securden Password Vault for Enterprises is a scalable, enterprise-grade credential management solution available in both cloud (SaaS) and on-premise deployments. It centralizes the storage of passwords, SSH keys, DevOps secrets, files, and other sensitive data in an AES-256 encrypted vault, helping organizations enforce strong security controls and defend against insider and external threats. The solution enables secure credential storage, granular access controls, automated password rotation, and just-in-time access while providing full visibility through audit logs, session recordings, and real-time alerts. IT teams can launch secure remote connections such as RDP, SSH, and SQL directly from the vault without exposing credentials. Trusted by enterprises worldwide, Securden helps organizations strengthen security posture, streamline credential governance, improve operational efficiency, and meet compliance requirements across industries.

Keeper Security is transforming the way people and organizations around the world secure their passwords and passkeys, secrets and confidential information. Keeper’s easy-to-use cybersecurity platform is built on a foundation of zero-trust and zero-knowledge security to protect every user on every device. Keeper’s solution deploys in minutes and seamlessly integrates with any tech stack to prevent breaches, reduce help desk costs and ensure compliance. Trusted by millions of individuals and thousands of organizations globally, Keeper is the leader for best-in-class password and passkey management, secrets management, privileged access, secure remote access and encrypted messaging. Protect what matters at KeeperSecurity.com.

Rocket® Secure Host Access is a security-first terminal emulation solution designed to protect access to critical host and mainframe applications. It extends modern identity and access management (IAM) controls directly to green screen environments. The platform enables phishing-resistant, passwordless authentication to reduce credential-based threats. Rocket Secure Host Access supports compliance with regulations such as HIPAA, PCI-DSS, and DORA. It works across desktop, web, and hybrid environments for flexible deployment and consolidated ongoing administration. Strong encryption standards like TLS 1.3 and SSH help safeguard sensitive data. The solution strengthens enterprise security without disrupting existing workflows.

Passwork is a password manager built for security-conscious organizations, available as both a self-hosted (on-premise) solution and a secure cloud service. Developed and headquartered in Europe (Barcelona, Spain), Passwork meets GDPR, NIS2, ENS and other European regulatory requirements by design. The self-hosted version stores all passwords and credentials exclusively on your own server. Double-layer AES-256 encryption (server-side and client-side) with zero-knowledge architecture ensures your data stays within your infrastructure. For organizations seeking instant deployment without infrastructure overhead, Passwork Cloud provides a fully managed SaaS option. Hosted in secure data centers in Germany, the cloud platform operates on the same zero-knowledge model. Passwork is ISO/IEC 27001 certified. Both deployment options are trusted by enterprises for secure password sharing, privileged access management, and centralized credential governance.

MedTrainer accelerates and simplifies healthcare workforce education, compliance, and credentialing. MedTrainer’s natively built software platform provides a seamless user experience that helps healthcare organizations thrive in managing their workforce. Learning: A healthcare-specific learning management system (LMS) enriched with thousands of education courses and resources created by subject matter experts to satisfy regulatory, accreditation requirements, and provide continuing education credit. Compliance: A technology solution that combines incident reporting, document, and policy management, and highly customizable reports to improve compliance. Credentialing: An end-to-end credentialing capability with automation, workflows, and centralized data to simplify the process and reduce costly delays. From PSV to provider enrollment and privileging, everything is in one platform with complete visibility.

Uniqkey: Protect every login. Access with confidence. Uniqkey is Europe’s trusted password and access management platform - purpose-built for companies that demand security, simplicity, and control. Engineered by European cybersecurity experts, our platform combines military-grade encryption with an effortless user experience. We remove complexity from everyday workflows, helping employees stay secure without slowing them down. From auto-filling 2FA codes to streamlining access across your cloud environment, Uniqkey keeps security frictionless and productivity high. With real-time visibility across your entire infrastructure, IT teams gain complete control over access rights, employee activity, and security scores - empowering them to defend against threats and drive compliance with confidence proactively. Seamlessly integrated with Microsoft and other core systems, Uniqkey makes provisioning and offboarding fast, automated, and secure.