Best Bioinformatics Software for Mac

OmicsBox is a leading bioinformatics solution that offers end-to-end data analysis of genomes, transcriptomes, metagenomes, and genetic variation studies. The application is used by top private and public research institutions worldwide and allows researchers to easily process large and complex data sets, and streamline their analysis process. It is designed to be user-friendly, efficient, and with a powerful set of tools to extract biological insights from omics data. The software is structured in different modules, each with a specific set of tools and functions designed to perform different types of analysis, such as de-novo genome assemblies, genetic variation analysis, differential expression analysis, and taxonomic classifications of microbiome data, including the functional interpretation and rich visualizations of results. The functional analysis module includes the popular Blast2GO annotation methodology and makes OmicsBox particularly suited for non-model organism research

Ruffus is a computation pipeline library for python. It is open-sourced, powerful and user-friendly, and widely used in science and bioinformatics. Ruffus is designed to allow scientific and other analyses to be automated with the minimum of fuss and the least effort. Suitable for the simplest of tasks. Handles even fiendishly complicated pipelines which would cause make or scons to go cross-eyed and recursive. No "clever magic", no pre-processing. Unambitious, the lightweight syntax which tries to do this one small thing well. Ruffus is available under the permissive MIT free software license. This permits free use and inclusion even within proprietary software. It is good practice to run your pipeline in a temporary, “working” directory away from your original data. Ruffus is a lightweight python module for building computational pipelines. Ruffus requires Python 2.6 or higher or Python 3.0 or higher.

Geneious Prime makes bioinformatics accessible by transforming raw data into visualizations that make sequence analysis intuitive and user-friendly. Simple sequence assembly and easy editing of contigs. Automatic annotation for gene prediction, motifs, translation, and variant calling. Genotype microsatellite traces with automated ladder fitting and peak calling and generates tables of alleles. Beautiful visualizations of annotated genomes and assemblies are displayed in a highly customizable sequence view. Powerful SNP variants analysis, simple RNA-Seq expression analysis, and amplicon metagenomics. Design and test PCR and sequencing primers and create your own searchable primer database. Powerful CRISPR tools make it easy to find sites, design guide RNAs, and analyze your editing results. Accurate downstream analysis with extensive NGS pre-processing tools producing clean sequence data. Build phylogenetic trees using peer-reviewed algorithms.

Qlucore Omics Explorer is so easy to use that you no longer have to depend on an expert in bioinformatics to explore and analyze your Omics and NGS data sets. Qlucore Omics Explorer is a D.I.Y next-generation bioinformatics software for research in life science, plant- and biotech industries, as well as academia. The powerful and flexible visualization-based data analysis tool with inbuilt powerful statistics delivers immediate results and provides instant exploration and visualization of big data. The software is developed to allow the workflow which best suits you and your experiments and maximizes the outcome of your research. By combining instant visualization with powerful statistics and flexible selection methods, you will be able to see your results immediately. As a user, you decide your own workflow and starting point. You are in control and can tailor the exploration to meet your specific needs.

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modeling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. Successful compounds require a balance of many different properties. StarDrop™ guides you through this multi-parameter optimization challenge to target compounds with the best chance of success, saving you time and resources by enabling you to synthesize and test fewer compounds.

Swiss-PdbViewer (aka DeepView) is an application that provides a user-friendly interface allowing to analysis of several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles, and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface. Swiss-PdbViewer (aka DeepView) has been developed since 1994 by Nicolas Guex. Swiss-PdbViewer was initially tightly linked to SWISS-MODEL, an automated homology modeling server developed within the Swiss Institute of Bioinformatics (SIB) at the Structural Bioinformatics Group at the Biozentrum in Basel. However, the SWISS-MODEL web interface evolved to a point where it is now possible to use it directly for advanced modeling. Maintaining a direct interface with Swiss-PdbViewer is too complex and no longer supported.

Avogadro is an advanced molecule editor and visualizer designed for cross-platform use in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. It offers flexible high quality rendering and a powerful plugin architecture. Avogadro is a free, open-source molecular editor and visualization tool, designed for use on Mac, Windows, and Linux in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. It offers flexible high quality rendering and a powerful plugin architecture.