Best Autonomous Endpoint Management (AEM) Software for Mac

NinjaOne unifies IT to simplify work for 35,000+ customers in 140+ countries. The NinjaOne Unified IT Operations Platform delivers endpoint management, autonomous patching, backup, and remote access in a single console to improve efficiency, increase resilience, and reduce spend. By automating IT and managing all endpoints, organizations give employees a great technology experience to work faster, smarter, and easier while IT teams modernize and improve efficiency. NinjaOne is a Leader in the Gartner Magic Quadrant for Endpoint Management Tools. The company is obsessed with customer success and has retained a 98% customer satisfaction score for more than 5 years.

Atera, the first and only Agentic AI platform for IT management, offers IT teams and MSPs a digital workforce of AI agents to preemptively and autonomously manage their entire IT operations. Its all-in-one platform combines RMM, helpdesk, ticketing, and automation to reduce downtime, improve SLAs, and free IT teams to focus on strategic work over mundane tasks. At the core of Atera’s platform are two powerful AI agents built to enhance every layer of IT operations. AI Copilot helps technicians troubleshoot devices, run diagnostics, and generate actionable solutions in real time. IT Autopilot delivers 24/7/365, autonomously resolving Tier-1 issues and reducing IT workload by up to 40%. It acts like a personal AI technician for every employee, freeing your team to focus on what really matters. Trusted by 13K+ customers in over 120 countries, Atera scales with your needs while maintaining the highest security and compliance standards.

ManageEngine Endpoint Central is built to secure the digital workplace while also giving IT teams complete control over their enterprise endpoints. It delivers a security-first approach by combining advanced endpoint protection with comprehensive management, allowing IT teams to manage the entire endpoint lifecycle, all from a single console. With automated patching across Windows, Mac, Linux and 1,000+ third-party applications, it ensures vulnerabilities are mitigated before attackers can exploit them. Its next-gen antivirus (NGAV) feature, powered by AI-driven behavioural detection, provides 24/7 protection against ransomware, malware, and zero-day threats. Endpoint Central further strengthens enterprise defenses with a broad set of security capabilities, including vulnerability assessment and mitigation, peripheral device control, data loss prevention, application control, endpoint privilege management, encryption with FileVault and BitLocker, and browser security.

Atera IT Autopilot is an autonomous AI agent designed to provide 24/7 IT support, helping IT teams manage rising ticket volumes and staff shortages. It automates routine and complex IT tasks, enabling users to self-solve issues and reducing the IT workload by up to 40%. The platform offers instant, always-on support with near-zero response times, ensuring minimal downtime and keeping employees productive. IT Autopilot interacts through multiple channels including a user portal, email, Slack, and Teams, delivering human-like assistance. It also provides smart device and cloud support, proactive IT solutions, and analytics reporting. This tool helps IT teams focus on priority projects by eliminating repetitive support tasks.

Action1 is an autonomous endpoint management platform trusted by many Fortune 500 companies. Cloud-native, infinitely scalable, highly secure, and configurable in 5 minutes—it just works and is always free for the first 200 endpoints, with no functional limits. By pioneering autonomous OS and third-party patching with peer-to-peer patch distribution and real-time vulnerability assessment without needing a VPN, it eliminates routine labor, preempts ransomware and security risks, and protects the digital employee experience. In 2025, Action1 was recognized by Inc. 5000 as the fastest-growing private software company in America. The company is founder-led by Alex Vovk and Mike Walters, American entrepreneurs who previously founded Netwrix, a multi-billion-dollar cybersecurity company.

Zirozen is a unified autonomous endpoint management platform that delivers real‑time visibility and control across your entire IT environment to network equipment and cloud infrastructure, via an intuitive drag‑and‑drop dashboard. Its AI‑powered engine continuously scans for vulnerabilities, misconfigurations, missing patches, and unauthorized software, automatically prioritizing and remediating risks based on severity scores. Zirozen automates cross‑platform patch and configuration management with policy‑driven scheduling, continuous compliance auditing for standards like GDPR, HIPAA, and PCI‑DSS, software metering and license optimization, file integrity monitoring, application control, and malicious activity detection. Deep integrations eliminate tool sprawl by correlating security, asset, and inventory data in one console, while customizable alerts and centralized reporting enable proactive SecOps with reduced mean time to resolution.

Iru (formerly Kandji) is an all-in-one, AI-powered security and compliance platform designed to simplify IT management and strengthen enterprise protection. Built on the Iru Context Model, it unifies identity, endpoint, and compliance into a single intelligent system that understands users, devices, and applications in context. With passwordless workforce identity, advanced endpoint detection, and automated compliance, Iru delivers both security and efficiency without the complexity of multiple tools. Its integrated approach enables IT teams to secure access, prevent threats, and maintain continuous audit readiness—all from one intuitive platform. Trusted by over 5,000 companies including Plaid, Notion, Airbus, and Vercel, Iru transforms how modern businesses manage digital trust. The result is reduced IT workload, improved employee experience, and enterprise-grade protection built for the AI era.

Cloud-native and globally available, Automox enforces OS & third-party patch management, security configurations, and custom scripting across Windows, Mac, and Linux from a single intuitive console. IT and SecOps can quickly gain control and share visibility of on-prem, remote and virtual endpoints without the need to deploy costly infrastructure.

Splashtop Autonomous Endpoint Management is an automation-led endpoint management solution designed to help IT teams monitor, secure, patch, and manage endpoints remotely with minimal manual effort by providing real-time visibility into device health, automated system and third-party software patching, and compliance tracking across distributed environments. It enables secure remote access, real-time patch management that complements tools like Microsoft Intune by detecting and remediating zero-day vulnerabilities, and centralized dashboards that show inventory, security metrics, and endpoint status, allowing IT operations to proactively fix issues before they impact users and maintain consistent compliance with regulations such as ISO/IEC 27001, SOC 2, GDPR, HIPAA, and PCI. AEM automates routine tasks such as patch deployment, system updates, and diagnostics, freeing IT staff from repetitive manual work, and supports advanced features.

"HCL BigFix: Secure Resilient Operations, Powered by AI HCL BigFix is the platform for unified endpoint and infrastructure management, purpose-built to deliver on the Digital+ promise of reducing cost, risk, and complexity. Proven at enterprise scale, BigFix secures and manages 155M+ endpoints across nearly 100 operating systems. It leverages AI-driven automation to deliver continuous compliance and real-time vulnerability remediation with one of the industry’s best first-pass patch success rates (>98%). This is enhanced by AEX, our agentic AI platform, which transforms the digital employee experience through proactive, self-healing support. HCL BigFix is the single solution to secure any endpoint, in any cloud, across any industry. "

Remedio is an AI-powered, autonomous device posture management platform that continuously discovers, monitors, and remediates security misconfigurations and configuration drift across enterprise IT and OT environments to reduce attack surface, enforce compliance, and harden endpoint security without disruption. It delivers real-time visibility into configuration risks on devices running Windows, macOS, and Linux, as well as cloud instances and servers, and automatically applies safe remediation actions that are instantly reversible, giving security teams confidence when closing gaps without business impact. Remedio simplifies policy validation and enforcement by benchmarking settings against security standards such as CIS, NIST, and MITRE frameworks and continuously re-applies policies across updates, user changes, and new devices to maintain consistent secure baselines. It provides centralized control and governance of Active Directory, Group Policy, MDM, and Intune settings.