Best Autonomous Endpoint Management (AEM) Software

NinjaOne unifies IT to simplify work for 35,000+ customers in 140+ countries. The NinjaOne Unified IT Operations Platform delivers endpoint management, autonomous patching, backup, and remote access in a single console to improve efficiency, increase resilience, and reduce spend. By automating IT and managing all endpoints, organizations give employees a great technology experience to work faster, smarter, and easier while IT teams modernize and improve efficiency. NinjaOne is a Leader in the Gartner Magic Quadrant for Endpoint Management Tools. The company is obsessed with customer success and has retained a 98% customer satisfaction score for more than 5 years.

Atera, the first and only Agentic AI platform for IT management, offers IT teams and MSPs a digital workforce of AI agents to preemptively and autonomously manage their entire IT operations. Its all-in-one platform combines RMM, helpdesk, ticketing, and automation to reduce downtime, improve SLAs, and free IT teams to focus on strategic work over mundane tasks. At the core of Atera’s platform are two powerful AI agents built to enhance every layer of IT operations. AI Copilot helps technicians troubleshoot devices, run diagnostics, and generate actionable solutions in real time. IT Autopilot delivers 24/7/365, autonomously resolving Tier-1 issues and reducing IT workload by up to 40%. It acts like a personal AI technician for every employee, freeing your team to focus on what really matters. Trusted by 13K+ customers in over 120 countries, Atera scales with your needs while maintaining the highest security and compliance standards.

ManageEngine Endpoint Central is built to secure the digital workplace while also giving IT teams complete control over their enterprise endpoints. It delivers a security-first approach by combining advanced endpoint protection with comprehensive management, allowing IT teams to manage the entire endpoint lifecycle, all from a single console. With automated patching across Windows, Mac, Linux and 1,000+ third-party applications, it ensures vulnerabilities are mitigated before attackers can exploit them. Its next-gen antivirus (NGAV) feature, powered by AI-driven behavioural detection, provides 24/7 protection against ransomware, malware, and zero-day threats. Endpoint Central further strengthens enterprise defenses with a broad set of security capabilities, including vulnerability assessment and mitigation, peripheral device control, data loss prevention, application control, endpoint privilege management, encryption with FileVault and BitLocker, and browser security.

Atera IT Autopilot is an autonomous AI agent designed to provide 24/7 IT support, helping IT teams manage rising ticket volumes and staff shortages. It automates routine and complex IT tasks, enabling users to self-solve issues and reducing the IT workload by up to 40%. The platform offers instant, always-on support with near-zero response times, ensuring minimal downtime and keeping employees productive. IT Autopilot interacts through multiple channels including a user portal, email, Slack, and Teams, delivering human-like assistance. It also provides smart device and cloud support, proactive IT solutions, and analytics reporting. This tool helps IT teams focus on priority projects by eliminating repetitive support tasks.

Action1 is an autonomous endpoint management platform trusted by many Fortune 500 companies. Cloud-native, infinitely scalable, highly secure, and configurable in 5 minutes—it just works and is always free for the first 200 endpoints, with no functional limits. By pioneering autonomous OS and third-party patching with peer-to-peer patch distribution and real-time vulnerability assessment without needing a VPN, it eliminates routine labor, preempts ransomware and security risks, and protects the digital employee experience. In 2025, Action1 was recognized by Inc. 5000 as the fastest-growing private software company in America. The company is founder-led by Alex Vovk and Mike Walters, American entrepreneurs who previously founded Netwrix, a multi-billion-dollar cybersecurity company.

Zirozen is a unified autonomous endpoint management platform that delivers real‑time visibility and control across your entire IT environment to network equipment and cloud infrastructure, via an intuitive drag‑and‑drop dashboard. Its AI‑powered engine continuously scans for vulnerabilities, misconfigurations, missing patches, and unauthorized software, automatically prioritizing and remediating risks based on severity scores. Zirozen automates cross‑platform patch and configuration management with policy‑driven scheduling, continuous compliance auditing for standards like GDPR, HIPAA, and PCI‑DSS, software metering and license optimization, file integrity monitoring, application control, and malicious activity detection. Deep integrations eliminate tool sprawl by correlating security, asset, and inventory data in one console, while customizable alerts and centralized reporting enable proactive SecOps with reduced mean time to resolution.

Power and protect your teams from cloud to edge with Ivanti Neurons, the hyperautomation platform for the Everywhere Workplace. Delivering the power of self-healing has never been so simple. What if you could discover and fix issues automatically before your users even know about them? Ivanti Neurons does just that. Powered by machine-learning and deep intelligence, it lets you remediate issues preemptively before they slow your productivity. Take troubleshooting off your agenda and deliver better experiences, everywhere your business works. Ivanti Neurons fuels your IT with real-time intelligence you can act on, enables devices to self-heal and self-secure, and provides users with a personalized self-service experience. Empower your users, your team and your business to do more, everywhere, with Ivanti Neurons. Ivanti Neurons delivers value from day one by providing real-time insights that let you thwart risks and prevent breaches in seconds, not minutes.

HCL BigFix AEX is a part of the Autonomous Endpoint Management pillar under the HCLSoftware Intelligent Operations ecosystem. It is a Generative AI-driven agent assist solution that offers intelligent self-service support, comprehends employee requests, and perpetually refines its responses for enhanced employee experience.​ It is designed to revolutionize enterprise service operations. AEX's intelligence approach empowers organizations to deliver exceptional support experiences, streamline operations, and increase overall productivity.

Empowering the world’s largest organizations to manage and protect their mission-critical networks. Our data model can collect new, ad-hoc data on the fly in seconds, allowing customers, partners and Tanium to quickly develop capabilities on this extensible platform. Our patented architecture collects and distributes data to millions of endpoints in seconds, with zero infrastructure. Enable decision-making where data is generated: the endpoint itself. Our agent consumes minimal endpoint resources and bandwidth while fitting on the firmware of the smallest chips. Expand your capabilities without expanding Tanium’s footprint. We’ve found that the best way for customers to understand what we do is to show our platform in action. Orion Hindawi, Tanium’s co-founder and CEO, will guide you through a hands-on keyboard tour to show what Tanium does and the power of the platform. Track down every IT asset you own instantaneously.

Iru (formerly Kandji) is an all-in-one, AI-powered security and compliance platform designed to simplify IT management and strengthen enterprise protection. Built on the Iru Context Model, it unifies identity, endpoint, and compliance into a single intelligent system that understands users, devices, and applications in context. With passwordless workforce identity, advanced endpoint detection, and automated compliance, Iru delivers both security and efficiency without the complexity of multiple tools. Its integrated approach enables IT teams to secure access, prevent threats, and maintain continuous audit readiness—all from one intuitive platform. Trusted by over 5,000 companies including Plaid, Notion, Airbus, and Vercel, Iru transforms how modern businesses manage digital trust. The result is reduced IT workload, improved employee experience, and enterprise-grade protection built for the AI era.

Cloud-native and globally available, Automox enforces OS & third-party patch management, security configurations, and custom scripting across Windows, Mac, and Linux from a single intuitive console. IT and SecOps can quickly gain control and share visibility of on-prem, remote and virtual endpoints without the need to deploy costly infrastructure.

Splashtop Autonomous Endpoint Management is an automation-led endpoint management solution designed to help IT teams monitor, secure, patch, and manage endpoints remotely with minimal manual effort by providing real-time visibility into device health, automated system and third-party software patching, and compliance tracking across distributed environments. It enables secure remote access, real-time patch management that complements tools like Microsoft Intune by detecting and remediating zero-day vulnerabilities, and centralized dashboards that show inventory, security metrics, and endpoint status, allowing IT operations to proactively fix issues before they impact users and maintain consistent compliance with regulations such as ISO/IEC 27001, SOC 2, GDPR, HIPAA, and PCI. AEM automates routine tasks such as patch deployment, system updates, and diagnostics, freeing IT staff from repetitive manual work, and supports advanced features.

"HCL BigFix: Secure Resilient Operations, Powered by AI HCL BigFix is the platform for unified endpoint and infrastructure management, purpose-built to deliver on the Digital+ promise of reducing cost, risk, and complexity. Proven at enterprise scale, BigFix secures and manages 155M+ endpoints across nearly 100 operating systems. It leverages AI-driven automation to deliver continuous compliance and real-time vulnerability remediation with one of the industry’s best first-pass patch success rates (>98%). This is enhanced by AEX, our agentic AI platform, which transforms the digital employee experience through proactive, self-healing support. HCL BigFix is the single solution to secure any endpoint, in any cloud, across any industry. "

Remedio is an AI-powered, autonomous device posture management platform that continuously discovers, monitors, and remediates security misconfigurations and configuration drift across enterprise IT and OT environments to reduce attack surface, enforce compliance, and harden endpoint security without disruption. It delivers real-time visibility into configuration risks on devices running Windows, macOS, and Linux, as well as cloud instances and servers, and automatically applies safe remediation actions that are instantly reversible, giving security teams confidence when closing gaps without business impact. Remedio simplifies policy validation and enforcement by benchmarking settings against security standards such as CIS, NIST, and MITRE frameworks and continuously re-applies policies across updates, user changes, and new devices to maintain consistent secure baselines. It provides centralized control and governance of Active Directory, Group Policy, MDM, and Intune settings.

Simply and securely deliver and manage any app on any device with Workspace ONE, an intelligence-driven digital workspace platform. Workspace ONE integrates access control, application management and multi-platform endpoint management into a single platform and is available as a cloud service or on-premises deployment. Enables enterprises to maximize employee engagement and productivity by empowering employees with a personalized experience and Day One access to any app on any device. Embrace a single, cloud-native solution for unified endpoint management—for any device and any use case. Eliminate silos and manage every device and app type faster, with fewer point solutions and more capabilities. Secure devices, users, and data with conditional access, automated patching, and configuration policies to achieve a comprehensive Zero Trust security approach.

Transform IT service delivery for your modern workplace. Simplify modern workplace management and achieve digital transformation with Microsoft Intune. Create the most productive Microsoft 365 environment for users to work on devices and apps they choose, while protecting data. Securely manage iOS, Android, Windows, and macOS devices with a single endpoint management solution. Streamline and automate deployment, provisioning, policy management, app delivery, and updates. Stay up to date with a highly scalable, globally distributed cloud service architecture. Leverage the intelligent cloud for insights and baselines for your security policies and configuration settings. Help safeguard data when you don’t manage devices used by employees or partners to access work files. Intune app protection policies provide granular control over Office 365 data on mobile devices.

Adaptiva OneSite Health automatically checks the configuration of endpoints, diagnoses any problems, and remediates any issues. And it does this at massive scale – hundreds of thousands of endpoints – without bandwidth throttling or disrupting business processes. Adaptiva OneSite Health is the fastest, most scalable solution to manage endpoint health at scale and includes over 100 pre-built checks and remediations. Our customers use Endpoint Health to ensure endpoints are functioning properly and securely. Over 100 built-in checks can ensure Bitlocker is turned on, or ConfigMgr is working as expected. A major national retailer ran Adaptiva OneSite Health on just over 11,000 live production endpoints. They found a 55% failure rate. Endpoint Health was able to automatically remediate 89% of failed endpoints, with an instant savings of over $1m.

Patchifi is a cloud-native autonomous endpoint management platform that automates patching, compliance, and software deployment to secure and maintain endpoint health for IT teams and MSPs without manual scripting, WSUS dependency, or complex infrastructure. It continuously scans endpoints to detect missing updates and deploys patches automatically with policy-driven automation, helping organizations close vulnerability gaps quickly, maintain real-time compliance, and minimize operational disruptions. It provides centralized dashboards with real-time visibility into patch status, system health, and compliance metrics, and generates audit-ready reporting to simplify regulatory assessments. Patchifi supports automated software deployment and configuration enforcement across hybrid workforces, enabling silent application installs, targeted rollouts, and consistent policy application regardless of network location.

Seamlessly manage and protect your devices across all operating systems (OS). IBM® MaaS360® is uniquely equipped to help IT professionals manage a wide variety of endpoints, apps, and data, and protect them efficiently and productively. MaaS360 offers unified endpoint management (UEM) capabilities such as: Streamlined enrollment: IT pros don’t need to touch devices to enroll them. The device setup is already configured in the MaaS360 pre-deployment phase, and corporate resources are handled by over-the-air provisioning. Simplified endpoint management: Manage virtually all device types and the main OS, such as Apple iOS, Android, iPadOS, Microsoft Windows, and Google ChromeOS, from a single console. Take advantage of the simple self-service provisioning process, same-day OS support for the latest platform and 24x7 support by chat, phone, and email.