Compare the Top AI IT Agents that integrate with Microsoft 365 as of April 2026

This a list of AI IT Agents that integrate with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.

What are AI IT Agents for Microsoft 365?

AI IT agents are autonomous or semi-autonomous software agents designed to monitor, manage, and resolve IT operations tasks using artificial intelligence. They can analyze signals from logs, metrics, tickets, and endpoints to detect issues and take corrective action in real time. These agents often collaborate with existing IT systems to automate incident response, remediation, and routine maintenance. Many AI IT agents learn from historical data to improve accuracy and decision-making over time. By reducing manual intervention and response times, AI IT agents enhance system reliability, security, and IT team productivity. Compare and read user reviews of the best AI IT Agents for Microsoft 365 currently available using the table below. This list is updated regularly.

  • 1
    Robin by Atera
    Robin by Atera is an autonomous IT support agent designed to automatically diagnose and resolve technical issues across devices and cloud environments. The system acts as an AI-powered IT assistant that manages support requests from start to finish without human intervention. Robin receives requests from platforms such as Slack, Microsoft Teams, email, and IT service management tools, verifies the user’s identity, and gathers technical context to understand the problem. It can then perform approved actions on devices, networks, or cloud systems to resolve the issue. By automating troubleshooting and IT support workflows, Robin helps organizations reduce downtime and improve support efficiency.
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  • 2
    SysAid

    SysAid

    SysAid Technologies

    SysAid is an AI-first Help Desk & ITSM platform powered by Agentic AI. It makes your IT team 100x more impactful, resolves issues faster, eliminates repetitive tasks, and shifts from firefighting to delivering strategic impact. With no-code workflows, AI-powered ticket handling, and an intuitive self-service portal, SysAid empowers IT to focus on what really matters: business value. At its core is Agentic AI: a powerful operational layer where AI Agents take the first action, accelerating resolution and boosting efficiency. Built for IT, SysAid includes enterprise-grade security, built-in governance, and the ability to add guardrails, control, and responsible AI protection to your data. Go live in weeks with fast, code-free onboarding—no heavy migrations or steep learning curves. With flexible customization and award-winning support, SysAid grows with you. ITSM run by AI, and by you.
  • 3
    Guru

    Guru

    Guru

    Guru is the AI Source of Truth for your company. It’s an AI knowledge platform that connects everything your teams know—across chats, docs, and apps—into one trusted layer that delivers cited, permission-aware answers everywhere you work. Guru automatically connects to tools like Slack, Teams, Google Drive, Confluence, Salesforce, Zendesk, and more, so employees and AI assistants can access verified knowledge directly in their workflow. Every answer shows where it came from, inherits existing permissions, and stays accurate automatically through built-in verification and expert updates. By connecting knowledge, making it accessible everywhere, and keeping it trustworthy automatically, Guru eliminates manual searches and ensures everyone—human or AI—works from the same truth.
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    Starting Price: $25
  • 4
    Rezolve.ai

    Rezolve.ai

    Rezolve.ai

    Rezolve.ai is a GenAI-enabled AITSM solution- a next evolution of ITSM that helps enterprises eliminate enterprise friction and increase employee productivity, often reaching an impressive 5%. Seamlessly integrated with Microsoft Teams, Rezolve.ai isn't just a service desk; it's a powerhouse for creating the next generation of IT service management (AITSM) with astounding business outcomes. It harnesses the incredible capabilities of Generative AI and automation to empower your technicians and service desk managers, turning them into IT support superheroes. Rezolve.ai AITSM solution can enhance your service desk efficiency by automating most of the repetitive IT service desk processes and tasks like password resets, request routing, and basic troubleshooting without human intervention. This reduces the workload on your service desk team and allows them to focus on more complex and high-value tasks.
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