Genetic variants alter cellular behavior in a variety of ways, changing biochemical properties of DNA, mRNA, and proteins. Many large-scale sequencing projects are under way to detect human variation in health and disease. Although broad disease associations can be discovered by GWAS studies, the low-level impact of mutations is hardly available in structured form. The results of thousands of small-scale experiments, on the other hand, are present in the literature and discuss observations made ranging from alteration of active sites to changes in drug response resulting.

Our aim is to bridge the gap between detection of genetic variants and their annotation with aforementioned observations. VarImpact extracts experimentally observed changes from the literature. This allows to annotate sequencing results with observed impacts, gather information about the mutational landscape observed in disease populations, and to study disease mechanisms.

Check our Wiki for more!

Project Activity

See All Activity >

Follow VarImpact

VarImpact Web Site

Other Useful Business Software
AI-powered service management for IT and enterprise teams Icon
AI-powered service management for IT and enterprise teams

Enterprise-grade ITSM, for every business

Give your IT, operations, and business teams the ability to deliver exceptional services—without the complexity. Maximize operational efficiency with refreshingly simple, AI-powered Freshservice.
Try it Free
Rate This Project
Login To Rate This Project

User Reviews

Be the first to post a review of VarImpact!

Additional Project Details

Intended Audience

Healthcare Industry, Science/Research

Programming Language

Java

Database Environment

JDBC, MySQL

Related Categories

Java Bio-Informatics Software, Java Medical Software, Java Machine Learning Software

Registered

2014-07-24