TI2BioP allows mainly the calculation of topological indices (spectral moments) derived from inferred and artificial 2D structures of DNA, RNA and proteins being possible to carry out a structure-function correlation irrespective of sequence alignments.
TI2BioP version 3.0 is a python platform with a graphical interface designed for Windows, Linux and Mac OS.

Features

  • DNA/RNA and protein sequences are arranged into an artificial 2D space
  • 2D-RNA folding information contained in Xfasta and CTs is imported
  • Spectral Moments as Topological Indices (TIs) are calculated from 2D artificial and more accurate DNA/RNA and protein graphs
  • TIs are used to develop alignment-free (AF) models for functional/structural annotation
  • TIs are also used to estimate (AF) distances for phylogenetic analyses

Project Samples

TI2BioP_Graphical_Interface

Project Activity

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Categories

Bio-Informatics

License

GNU General Public License version 2.0 (GPLv2)

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TI2BioP Web Site

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Additional Project Details

Operating Systems

Linux, Windows, WINE

Intended Audience

Education, Science/Research

User Interface

Gnome, Win32 (MS Windows)

Programming Language

Delphi/Kylix, Python

Related Categories

Python Bio-Informatics Software, Delphi/Kylix Bio-Informatics Software

Registered

2011-07-27
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