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Short linear motifs / domains (SLiM) facilitate the functions and interactions of the proteins. Finding functional motifs in protein sequences could predict the putative cellular roles or characteristics of hypothetical proteins. ShettiMotif, which is an interactive tool to (i) searches for motifs containing repeated residues (e.g. Leu-, SR-, PEST-rich motifs, etc.), (ii) searches for multiple pre-defined consensus patterns or experimentally validated functional motifs in large datasets protein sequences (proteome-wide), (iii) map UniProt and PROSITE flat files. ShettiMotif can parse large dataset of sequences efficiently.

Article:
Haitham Sobhy; A bioinformatics pipeline to search functional motifs within whole proteome data; poxviruses a case study; Virus Genes, 2017; doi: 10.1007/s11262-016-1416-9; PMID:

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2015-08-17
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