PTM-X

The PTM-X (PTM cross-talk) project is a freely available bioinformatics software platform that allows to calculate the features of PTM pairs and the posterior probabilities of being cross-talk pairs. The prediction model is a naive Bayse classifier that integrats five features: protein sequence distance, tertiary structural distance, co-location in a disordered region, residue co-evolution, and modification co-evolution. An online tool is also available at http://bioinfo.bjmu.edu.cn/ptm-x/.